An efficient protocol for the synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives via multi-component coupling reaction of aromatic aldehydes, β-ketoester and urea or thiourea under solvent-free conditions using Silica Supported Barium Chloride as a catalyst is described. All prepared compounds with melting points, IR,1H NMR and 13C NMR were identified. High yields, mild conditi...

Some of appropriate aminoisopropanoloxy derivatives of 4-xanthone were tested for their effect on circulatory system (protection against adrenaline-, barium-, and calcium chloride-induced arrhythmias, as well as hypotensive activity and acute toxicity). The most prominent hypotensive activity was demonstrated by (+/-)-1-[4-(hydroxyethyl)-1-(piperazinyl)]-3-(4-xanthonoxy)-2-propanol dihydrochlor...

Bis(1,4-diamino-1,2,4-triazolium) sulfate (1) was obtained from the corresponding chloride by ion metathesis using Ag2SO4. Further metathesis with barium 5,51-azotetrazolate yielded bis(1,4-diamino-1,2,4-triazolium) 5,51-azotetrazolate (2). Numerous NH ̈ ̈ ̈N and NH ̈ ̈ ̈O interactions were identified in the crystal structures of 1 and 2. Both compounds undergo exothermal decomposition upon heating.

The 5-amino-(cyanoformimidoyl)-1H-imidazole has been prepared from amidine by treatment with barium hydroxide in ethanol. 2-(4-Isopropylbenzyl)-6-carbamoyl-1, 2-dihydropurine was obtained from 5-amino-4-(cyanoformimidoyl)-1H-imidazole and isopropylbenzaldehyde in dry methanol. All compounds have been fully characterized by spectroscopic data.

The reaction mixture of magnesium chloride with two equivalents of potassium anthranilate [K+ AnthÐ] in water gives on cooling to 0 ∞C a 60% yield of a precipitate which after drying in a vacuum has the composition [Mg(H2O)6](Anth)2 (1). Recrystallization from hot water affords an octahydrate identified as [Mg(H2O)6](Anth)2(H2O)2 (2) in a single crystal X-ray diffraction study. Contrary to find...

The article presents the results of a study thermodynamic-diagram analysis Fe-Si-Al-Ba multicomponent system, where, on basis thermodynamic data, boundary ternary systems basic four-component system are constructed. As result, it was determined that consists 12 elementary tetrahedra. For each tetrahedra, analytical equations determined, with help which is possible to establish location in facto...

A six new analogs of MG-1(S), 1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl]-pyrrolidin-2-one, with adrenolytic properties were tested for electrocardiographic and antiarrhythmic activity in model ventricular arrhythmias associated with coronary artery occlusion and reperfusion in the non-working isolated perfused rat heart and additionally in barium chloride-induced arrhythmia in vivo. All tes...

In our attempt to search for mixed alkaline-earth and transition metal arsenates, the title compound, barium dimanganese(II) bis-(arsenate), has been synthesized by employing a high-temperature RbCl flux. The crystal structure of BaMn2(AsO4)2 is made up of MnO6 octa-hedra and AsO4 tetra-hedra assembled by sharing corners and edges into infinite slabs with composition [Mn2(AsO4)2]2- that extend ...