Considering unsaturation conditions of soil significantly helps to produce relatively real results. Numerical methods have been assumed as conventional methods in soil mechanics to examine soil behavior. However, the accuracy of numerical methods dramatically depends on applying the appropriate behavioral model to solve problems. One of the known elastoplastic models for unsaturated soils i...

the vehicle driving comfort has become one of the important factors of vehicle quality and receives increasing attention. in this paper, optimal points of vehicle suspension parameters are generated using modified non-dominated sorting genetic algorithm (nsga-ii) for pareto optimization of 5-degree of freedom vehicle vibration model considering three conflicting functions simultaneously. in thi...

QUESTIONS UNDER STUDY/PRINCIPLES A retrospective assessment of long-term results on a single centre, single author experience in treating prostate cancer with high dose curative radiotherapy (RT) with or without androgen deprivation (AD). METHODS Between 1991 and 2004, 408 patients with clinically localised prostate cancer were treated with RT (+/-AD) at the University Hospital of Geneva. RT ...

While the prognostic value of DNA ploidy has been well established for radical prostatectomy, external beam radiation, brachytherapy and androgen deprivation therapy its role as a survival outcome predictor for prostate cancer patients treated with cryoablation has not yet been examined. Anecdotal evidence suggesting that cryoablation may be independent of DNA ploidy type led to the implementat...

in this paper, multi-objective uniform-diversity genetic algorithm (muga) with a diversity preserving mechanism called the ε-elimination algorithm is used for pareto optimization of 5-degree of freedom vehicle vibration model considering the five conflicting functions simultaneously. the important conflicting objective functions that have been considered in this work are, namely, vertical accel...

BACKGROUND The role of dose escalation in patients receiving long-term androgen deprivation therapy (ADT) is still a controversial issue. The aim of the current study was to evaluate whether dose escalation for ≥76-80 Gy had any advantage in terms of biochemical disease-free survival (BDFS), distant metastasis-free survival (DMFS), or overall survival outcomes over the dose levels from 70 to <7...

OBJECTIVE To evaluate the effect of neoadjuvant androgen deprivation therapy (NADT) on the outcomes for primary whole gland prostate cryoablation (CRYO). NADT before CRYO has sometimes been used for prostate volume reduction, with some theoretical benefit toward improving disease control. NADT has been shown to be beneficial for biochemical disease-free survival (bDFS) with radiotherapy but not...