The objective of this research was to investigate the influence of the over-expression of recombinant interferon-g during high cell density cultivation on cellular characteristics of recombinant E. coli. Batch and fed-batch culture techniques were employed to grow Escherichia coli BL21 for production of human gamma-interferon in pET expression system. Final cell densities in batch and fed-batch...

Flexible manufacturing system (FMS) readily addresses the dynamic needs of the customers in terms of variety and quality. At present, there is a need to produce a wide range of quality products in limited time span. On-time delivery of customers’ orders is critical in make-to-order (MTO) manufacturing systems. The completion time of the orders depends on several factors including arrival rate, ...

A single-server queueing model with infinite buffer and batch arrival of customers is considered. In contrast to the standard batch arrival when a whole batch arrives into the system at one epoch, we assume that the customers of an accepted batch arrive one by one in exponentially distributed times. Service time is exponentially distributed. Flow of batches is the stationary Poisson arrival pro...

This study seeks to investigate the effect of restricted feeding regimes at different rate on growth performance of Clarias gariepinus using static and flow through system. Fingerlings were divided into six batches for each systems with the first and second batch fed at 5% body weight (BW) every day and every other day respectively, the third and fourth batch were fed 10% BW every day and every...

We discuss dynamic system performance evaluation in the river port utilizing queuing models with batch arrivals. The general models of the system are developed. This system is modelled by M/M/n/m queue with finite waiting areas and identical and independent cargo-handling capacities. The models are considered with whole and part batch acceptance or whole and part batch rejections and the intera...

We propose a traffic measurement system which uses trap and polling methods. To obtain its performance we consider a queueing model with a single server and evaluate a packet delay. In our multi-cast traffic, packets are modeled as a batch with a batch size distribution {gk}. The batch arrival process is observed as two processes on the basis of batch size. For a batch whose size is more than o...

A novel high-density yeast propagation system has been developed, which produced that performed as well cropped in commercial brewery trials. This process is capable of producing concentrations 13 times greater than traditional approaches used breweries to date. The based on a controlled fed-batch fermentation, can produce pitching little 24 h. demonstrator plant was installed regional and from...

Batch size is an important issue in a supply chain system. It affects stock, cost, and service quality. This paper presents a batch-size decision method to determine the optimal batch size for a supply chain system. The goal of this method is to minimize the total cost of a supply chain at a reasonable service level. The proposed method first applies a mathematical model to finding the possible...