the objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (dds) for metoprolol tartarate (mt) as tablet and capsule. pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery ...

Distance and centrality computations are important building blocks for modern graph databases as well as for dedicated graph analytics systems. Two commonly used centrality metrics are the compute-intense closeness and betweenness centralities, which require numerous expensive shortest distance calculations. We propose batched algorithm execution to run multiple distance and centrality computat...

since hospitals are an important and integral part of the overall health delivery system, this study was carried out to measure the effectiveness of this institution within the system. the records of 633 hospitalized patients in the pediatrics ward of ghaem hospital in mashhad during 1357 (21 march 1978-20 march 1979) has been consulted. more than half of the patients were hospitalized with the...

We introduce and study the batched bin packing problem (BBPP), a bin packing problem in which items become available for packing incrementally, one batch at a time. A batched algorithm must pack a batch before the next batch becomes known. A batch may contain several items; the special case when each batch consists of merely one item is the well-studied on-line bin packing problem. We obtain lo...

In e-commerce markets, on time delivery is of great importance to customer satisfaction. this paper, we present a Deep Reinforcement Learning (DRL) approach for deciding how and when orders should be batched picked in warehouse minimize the number tardy orders. particular, technique facilitates making decisions whether an order individually (pick-by-order) or batch with other (pick-by-batch), i...

Scalable group rekeying is one of the important problems that needs to be addressed in order to support secure communications for large and dynamic groups. One of the challenging issues that arises in scalable group rekeying is the problem of delivering the updated keys to the members of the group in a reliable and timely manner. In this paper, we present a new scalable and reliable key distrib...

This paper presents a new scheduling algorithm RAD, and shows that RAD efficiently schedules batched parallel jobs on multiprocessors. An early result by Deng et al. shows that Dynamic Equi-partitioning is 4-competitive for mean response time when the number of jobs is not more than the number of processors. Then, in STOC 97, Edmonds et al. show that the mean response time obtained by Equi-part...

| In an on-demand video system, requests for a video le arriving within a period of time can be batched together and served with a single multicast stream; thereby reducing the bandwidth requirement compared with the un-batched case. In this paper, we study various batching schemes to meet delay and prootability requirements | in the window-size based and moving-average schemes, maximum and ave...

Content delivery has become an important application in the Internet. \Content" in this context can be a range of objects from movies to web pages to software distribution. A streaming content delivery server should provide nearly immediate and continuous service by provisioning suucient server and local network resources for the duration of playout. Because of the resource implications of deli...