granular cell tumor is a rare benign neoplasm most commonly appears in the head and neck region, especially in the tongue, cheek mucosa, and palate. occurrence in limbs is even rarer. these tumors account for approximately 0.5% of all soft tissue tumors. granular cell tumor can also affect other organs including skin, breast, and lungs. local recurrence and metastasis is potentially higher in m...

background: we conducted our study on 1110 patients with breast masses in order to investigate different aspects of power doppler sonography (pds) for differentiating between benign and malignant breast lesions and their prognostication. materials and methods: this study was conducted on the women who were referred to the sonography units of university hospitals for breast sonography and had a ...

Objective(s): MicroRNAs (miRs) are a class of small non-coding RNAs which are associated with tumor growth and progression. In the present study, we assessed the expression of selected miRs in malignant, benign, and adjacent normal breast tissues. Materials and Methods: The expression of miR-1297, miR-3191-5P, miR-4435, and miR-4465 were...

Background: Shear wave elastography (SWE) estimates the stiffness of a mass based on the velocity of shear wave propagation by sound waves. Due to higher cell density and angiogenesis, malignant masses have higher stiffness than benign ones. Methods: The present study was a prospective study and was performed on patients who were referred to Ahvaz Golestan Hospital with breast mass during Marc...

background : breast carcinoma is the most common malignant tumor and leading cause of cancer deaths in women. while fine needle aspiration cytology is highly accurate in the diagnosis of breast lesions, it possesses certain drawbacks. in those circumstances intraoperative imprint cytology assumes importance, however, imprint cytology is subjected to interpretative errors. computer image analysi...

Phyllodes tumors are rare fibroepithelial neoplasms of the breast, classified as benign, borderline, or malignant based on histological features. Osseous metaplasia, characterized by presence bone formation within tumor, is an uncommon finding. This case report highlights rarity osseous metaplasia in a benign phyllodes tumor. A 23-year-old female presented with gradually enlarging lump left bre...

conclusion our preliminary results have shown that although there is some overlap between benign and malignant tumors, adding dwi, mr imaging to routine soft tissue tumor protocols may improve diagnostic accuracy. results there was only one patient with a malignant cystic tumor and was not included in the statistical analysis. the median adc values of benign and malignant tumors were 2.31 ± 1.2...

dermatofibrosarcoma protuberans is an uncommon malignant mesenchymal tumor of the dermis, which most commonly appears on the body and extremities. a preoperative diagnosis of dermatofibrosarcoma protuberans is extremely difficult, because it is a very rare entity and its appearance is often similar to that of benign breast lesion. here, we presented a case of breast dermatofibrosarcoma protuber...

Physical examination and mammography are currently the only proven and reliable methods of early detection of breast cancer. Although, both procedures are highly sensitive, their limited specificity often requires surgical biopsy in order to differentiate between malignant and benign lesions.Palpable mass abnormalities of breast are often difficult to evaluate mammographically, especially in pa...

background: primary leiomyosarcoma (lms) of the breast is a very rare neoplasm of the breast arising from the mesenchymal tissue. the clinical presentation of this entity simulates other benign and malignant lesions of mesenchymal tissue of the breast. case presentation: case 1: a 40-year-old female presented with a right-sided breast lump, which was suspected to be a malignant spindle cell tum...