Benzimidazoles are among the most important nitrogen-containing heterocyclic compounds that have many pharmaceutical applications; including, antitumor, anticancer, anticorrosive, antibacterial, irritant and enzymatic interceptors. In this research, the synthesis of benzimidazoles using o-phenylenediamine and aldehyde derivatives in the presence of the nano montemurillonite in solvent-...

Benzimidazoles are the organic compounds investigated in this work. The experimental determination of the pKa values of protonated benzimidazoles in water is a challenge because of their low solubility. In addition, some derivatives are involved in tautomeric equilibria which increase the complexity of the theoretical pKa determinations. In the present study, different approaches are considered...

A novel method was proposed for the determination of five benzimidazoles (oxfendazole, mebendazole, flubendazole, albendazole, and fenbendazole) using magnetic graphene (G-Fe3O4). G-Fe3O4 was synthesized via in situ chemical coprecipitation. The properties of G-Fe3O4 were characterized by various instrumental methods. G-Fe3O4 exhibited a great adsorption ability and good stability towards analy...

There are very few resistance records on cattle nematodes. South American successive records have been increasing rapidly since the year 2000. In Argentina, increasing dissatisfaction based on the exclusive use of macrocyclic lactones has prompted the use of benzimidazoles in the Pampean region. The studied farm is located in the Argentina humid Pampas and had apparently poor results after anth...

This paper reports the (1)H, (13)C and (15)N NMR experimental study of five benzimidazoles in solution and in the solid state ((13)C and (15)N CPMAS NMR) as well as the theoretically calculated (GIAO/DFT) chemical shifts. We have assigned unambiguously the "tautomeric positions" (C3a/C7a, C4/C7 and C5/C6) of NH-benzimidazoles that, in some solvents and in the solid state, appear different (bloc...

SnCl4/nano-sawdust was prepared as a carbohydrate-based catalyst containing of tin bearing cellulose units. The catalyst was characterized by X-ray diffraction (XRD), fourier transform infrared spectroscopy (FT-IR), field emission scanning electron microscopy (FESEM) and energy dispersive X-ray spectroscopy (EDS). The catalyst was applied successfully as a readily available, inexpensive, biodeg...

Objetivo. Se evaluó la eficacia antihelmítica de albendazol y levamisol sobre poblaciones Strongyloides sp. en bucerros (Bubalus bubalis) con infecciones naturales el trópico Mexicano. Materiales Métodos. incluyeron 45 bucerros, que fueron distribuidos tres grupos experimentales acuerdo a excreción huevos por gramo heces (HPG) (n=15): a) Grupo control: sin desparasitación, b) BZ (benzimidazoles...

BACKGROUND The single-dose benzimidazoles used against Trichuris trichiura infections in humans are not satisfactory. Likewise, the benzimidazole, fenbendazole, has varied efficacy against Trichuris suis whereas Oesophagostomum dentatum is highly sensitive to the drug. The reasons for low treatment efficacy of Trichuris spp. infections are not known. METHODOLOGY We studied the effect of fenbe...