In the title compound, C(20)H(13)ClO(2)S, the O atom and the phenyl group of the phenyl-sulfinyl substituent lie on opposite sides of the plane of the benzofuran fragment; the S-bound phenyl ring is nearly perpendicular to this plane [80.87 (5)°]. The phenyl ring in the 2-position is rotated out of the benzofuran plane, making a dihedral angle of 17.43 (7)°. The crystal structure features π-π i...

The title compound, C(15)H(12)O(2)S, was prepared by the oxidation of 2-methyl-3-phenyl-sulfanyl-1-benzofuran with 3-chloro-peroxy-benzoic acid. The O atom and the phenyl group of the phenyl-sulfinyl substituent lie on opposite sides of the plane of the benzofuran system. The phenyl ring makes a dihedral angle of 78.76 (4)° with the benzofuran mean plane. The crystal structure is stabilized by ...

In the title compound, C(20)H(12)ClFO(2)S, the O atom and the phenyl ring of the phenyl-sulfinyl substituent lie on opposite sides of the plane of the benzofuran fragment; the phenyl ring is almost perpendicular to this plane [82.44 (5)°]. The 4-fluoro-phenyl ring is rotated out of the benzofuran plane, making a dihedral angle of 20.83 (6)°.

The title compound, C(15)H(12)O(2)S, was prepared by the oxidation of 3-methyl-sulfanyl-2-phenyl-1-benzofuran with 3-chloro-peroxy-benzoic acid. The phenyl ring makes a dihedral angle of 37.65 (8)° with the plane of the benzofuran fragment. The O atom and the methyl group of the methyl-sulfinyl substituent lie on opposite sides of the plane of the benzofuran ring system. The crystal structure i...

In the title compound, C(22)H(17)FOS, the crystal studied was an inversion twin with a 0.42 (18):0.58 (18) domain ratio. The 4-fluoro-phenyl ring is rotated out of the benzofuran plane, making a dihedral angle of 17.82 (6)°, and the dihedral angle between the 5-phenyl ring and the benzofuran plane is 29.45 (7)°.

In the title compound, C(21)H(15)ClOS, the 4-chloro-phenyl ring is rotated out of the benzofuran plane, making a dihedral angle of 21.50 (6)°. The dihedral angle between the 5-phenyl ring and the benzofuran plane is 29.39 (6)°. The crystal studied was an inversion twin with a 0.65 (7):0.35 (6) domain ratio.

Benzofurans display a wide array of pharmaceutical activities. The present work incorporates the synthesis some novel benzofuran derivatives. compound 1 (z)-3-amino-7methoxy-N1-(2-oxoindolin-3-yliedene)benzofuran-2-carbohydrazide was synthesized by refluxing carbohydrazide and isatin. formed key intermediate for compounds 2a-c. structures prepared derivatives were established physical spectral ...

In the title compound, C(22)H(18)OS, the 2-phenyl ring is rotated out of the benzofuran plane, making a dihedral angle of 29.18 (6)°. The dihedral angle between the 5-phenyl ring and the benzofuran plane is 20.42 (5)°. In the crystal structure, mol-ecules are linked by weak inter-molecular C-H⋯π inter-actions.

A highly enantioselective Michael addition reaction of 2-substituted benzofuran-3(2H)-ones to nitroolefins was promoted by a bifunctional squaramide catalyst. As a result, a number of chiral 2,2'-substituted benzofuran-3-one derivatives, bearing adjacent quaternary-tertiary stereocenters, were efficiently synthesized with excellent enantioselectivities.

In the title compound, C(15)H(10)ClFO(2)S, the O atom and the methyl group of the methyl-sulfinyl substituent are located on opposite sides of the plane through the benzofuran fragment. The 4-chloro-phenyl ring is rotated out of the benzofuran plane, as indicated by the dihedral angle of 21.04 (4)°. The crystal structure exhibits a weak inter-molecular C-H⋯O hydrogen bond and a Cl⋯O halogen bon...