نتایج جستجو برای: berlin definition
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VALID AND RELIABLE DEFINItions are essential to conduct epidemiological studies successful ly and to facilitate enrollment of a consistent patient phenotype into clinical trials. Clinicians also need such definitions to implement the results of clinical trials, discuss prognosis with families, and plan resource allocation. Following the initial description of acute respiratory distress syndrome...
INTRODUCTION The Berlin definition divides acute respiratory distress syndrome (ARDS) into three severity categories. The relationship between these categories and pulmonary microvascular permeability as well as extravascular lung water content, which is the hallmark of lung pathophysiology, remains to be elucidated. The aim of this study was to evaluate the relationship between extravascular l...
AIM Accurate biomarkers of the acute respiratory distress syndrome (ARDS) may help risk stratification and management. We assessed the relation between several biomarkers and the severity, course and outcome of late onset ARDS in 101 consecutive critically ill patients with new onset fever. MATERIALS AND METHODS On study days 0, 1, 2 and 7 we measured angiopoietin-2 (ANG2), pentraxin-3 (PTX3)...
In 1994, an American-European Consensus Conference (AECC) formalized the criteria for the diagnosis of the acute respiratory distress syndrome (ARDS). Although that definition is simple to apply in the clinical setting, it has been challenged over the years in several studies since the assessment of the oxygenation defect does not require standardized ventilatory support. We were the first to p...
Villar et al. [1] suggest four methodological sources of “bias” that could have led to an overestimation of the acute respiratory distress syndrome (ARDS) incidence in the LUNG SAFE study [2]. First, they suggest that an “unvalidated algorithm” was used to classify patients with ARDS. We simply utilized the Berlin Definition for ARDS [3]. When the Berlin criteria were met, patients were classif...
The initial hypoxemic level of acute respiratory distress syndrome (ARDS) defined according to Berlin definition might not be the optimal predictor for prognosis. We aimed to determine the predictive validity of the stabilized ratio of partial pressure arterial oxygen and fraction of inspired oxygen (PaO2/FiO2 ratio) following standard ventilator setting in the prognosis of patients with ARDS.T...
The hypergraph assignment problem (HAP) is the generalization of assignments from directed graphs to directed hypergraphs. It serves, in particular, as a universal tool to model several train composition rules in vehicle rotation planning for long distance passenger railways. We prove that even for problems with a small hyperarc size and hypergraphs with a special partitioned structure the HAP ...
Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité – Universitätsmedizin Berlin, Germany; Division of Medical Biotechnology, Paul-Ehrlich-Institut-Federal Institute for Vaccines and Biomedicines, Paul-Ehrlich-Straße 51-59, Langen, 63225, Germany; Department of Nephrology and Internal Intensive Care, Charité – Universitätsmedizin Berlin, Germany Correspondence:Mohamed Abou-El-E...
The recent Berlin definition has made some improvements in the older definition of acute respiratory distress syndrome (ARDS), although the concepts and components of the definition remained largely unchanged. In an effort to improve both predictive and face validity, the Berlin panel has examined a number of additional measures that may reflect increased pulmonary vascular permeability, includ...
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