The concentrations of clobetasone butyrate and betamethasone were measured in aqueous humour of patients undergoing cataract extraction 12.5 to 18.5 hours after application into the lower conjunctival sac of an ointment containing 0.1% of the steroid. Samples were assayed from 10 patients receiving clobetasone butyrate and 13 patients receiving betamethasone phosphate. There were measurable con...

BACKGROUND/AIM To compare estrogen and betamethasone in the topical treatment of labial adhesions in prepubertal girls. MATERIALS AND METHODS In this retrospective study, we evaluated 39 girls with labial adhesions covering at least 50% of the vaginal opening. Of the total patients, 20 were treated with a topical estrogen preparation, while the remaining 19 patients were treated with a combin...

The objective of this study was to determine the consequences for HPA axis functioning among healthy full-term newborns of prenatal treatment with the synthetic glucocorticoid (GC), betamethasone, which is the routine treatment for threatened preterm delivery. Ninety full-term infants were recruited into two study groups (30 betamethasone treated; 60 comparison group matched for GA at birth and...

Introduction: Postoperative sore throat is a common complaint in patients with endotracheal intubation and has potentially dangerous complications. This randomized controlled trial study investigated the incidence of postoperative sore throat after general anesthesia when betamethasone gel is applied to a tracheal tube compared with when IV dexamethasone is prescribed.   Materials and Methods: ...

i ntroduction: calcium hydroxide (ch) is one of the most common intracanal medications. corticosteroids (cs) are used in endodontics because of their anti-inflammatory activity. this study aimed to evaluate the antimicrobial effect of ch+betamethasone and ch+saline against enterococcus faecalis ( e. faecalis ) using agar diffusion test and measuring the microbial zone of inhibition (zoi). metho...

OBJECTIVES To determine if antenatal exposure to betamethasone for the prevention of neonatal respiratory distress syndrome alters psychological functioning and health related quality of life in adulthood. DESIGN Follow-up of the first and largest double blind, placebo controlled, randomised trial of a single course of antenatal betamethasone for the prevention of neonatal respiratory distres...

PURPOSE This study compares the effect of topical diclofenac with that of betamethasone against postoperative increase of intraocular pressure (IOP) after cataract surgery in normal patients, and also investigated the risk factors for postoperative increase of IOP in each group. METHODS Fifty consecutive patients without systemic disease who have bilateral and symmetrical cataracts underwent ...

STUDY OBJECTIVE Standard treatment for girls with labial fusion has included topical estrogen cream, manual separation, or surgery. Side effects may limit the use of topical estrogen. Betamethasone has recently shown efficacy at separating labial fusion. Local irritation and inflammation may be an initiator of labial fusion. No adverse effects of betamethasone treatment have been documented. Lo...

The intended purpose of this work is to develop and validate a dissolution test for betamethasone acetate and betamethasone sodium phosphate injectable suspension using a reverse-phase liquid chromatographic method. After testing sink conditions, dissolution medium and stability of the drug, the best conditions were: flow through cell of diameter 22.6 mm, 2.0 ml per minutes flow rate for 120 mi...