نتایج جستجو برای: binding cassette transporter

تعداد نتایج: 464028  

Journal: :International Journal of Molecular Sciences 2015

Ahmad Mohamad Zaki, Amel Sobhy El Sedfy, Heba Gaber El-Sheredy, Ola Hussein Elgaddar, Sara Ahmed Aglan,

Background: ATP-binding cassette membrane transporter G2 (ABCG2) gene is one of transporter family and well characterized for their association with chemoresistance. Promoter methylation is a mechanism for regulation of gene expression. O6-Methyl guanine DNA methyl transferase (MGMT) gene plays a fundamental role in DNA repair. MGMT has the ability to remove alkyl adducts from DNA at the O6 pos...

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2013

Journal: :Gene Reports 2021

Marine organisms are naturally equipped with multixenobiotic resistance mechanisms that often governed by ATP-binding cassette (ABC) transporter family members. Previous studies focused on the target genes of ABC but little is known about functionality their promoter regions. Due to importance promoters in gene regulation, we functionally characterized three major xenobiotic zebrafish, namely A...

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