The bio-barcode amplification assay has become a powerful tool in detecting tens to hundreds of biological targets such as proteins and nucleic acids in the entire sample. However, current bio-barcode detection schemes still require many experimental steps including microarrayer-based immobilization of oligonucleotides on a glass chip, silver enhancement of immobilized gold nanoparticles on a c...

The purpose of the present study was to formulate and evaluate donepezil loaded bio-nanoparticles for effective treatment of Alzheimer’s disease. For the preparation of bio-nanoparticles biomaterial was isolated from fruits of Carica papaya by an economic method. The biomaterial recovered from the concentrate was subjected for various physicochemical properties like color, solubility, ...

   In recent years, Hyperthermia has been used as an emerging technique for cancer treatment, especially for localized tumors. One of the promising cancer treatment approaches is magnetic nanoparticle (MNPs) Hyperthermia. In this theoretical work, the temperature distribution of a common tumor over the different sizes of Fe3O4 magnetic nanoparticles, namely 25, 50, 100, and 200 nm, was stud...

If a suspension of magnetic micron-sized and nano-sized particles is subjected to a homogeneous magnetic field, the nanoparticles are attracted to the microparticles and form thick anisotropic halos (clouds) around them. Such clouds can hinder approach of microparticles and result in effective repulsion between them [Lopez-Lopez et al. Soft Matter, 6, 4346 (2010)]. In this paper, we present det...

New understandings in the amorphous calcium carbonate nanoparticle synthesis lead to a final mass concentration increase by factor of 3.5. The stabilisation aqueous media is achieved 2-minute scalable process using bio-sourced stabilisers.

In an effort to prevent the formation of pathogenic biofilms on hydroxyapatite (HA)-based clinical devices and surfaces, we present a study evaluating the antimicrobial efficacy of Spherical biogenic Se-Nanostructures Embedded in Organic material (Bio Se-NEMO-S) produced by Bacillus mycoides SelTE01 in comparison with two different chemical selenium nanoparticle (SeNP) classes. These nanomateri...

To increase the flexibility of surface-attached bio-relevant ligands on gold nanoparticle (NP), hetero-bifunctional poly(ethylene glycol) (PEG), was synthesized having two different functional groups on both the terminals. Coumarin was conjugated to the gold NP through the PEG spacer. The results of cellular cytotoxicity and fluorescence microscopy showed that these NPs were non-toxic and could...