Epigenetic processes participate in cancer development and likely influence cancer prevention. Global DNA hypomethylation, gene promoter hypermethylation and aberrant histone post-translational modifications are hallmarks of neoplastic cells which have been associated with genomic instability and altered gene expression. Because epigenetic deregulation occurs early in carcinogenesis and is pote...

One of the greatest challenges food research is facing in this century lies in maintaining sustainable food production and at the same time delivering high quality food products with an added functionality to prevent life-style related diseases such as, cancer, obesity, diabetes, heart disease, stroke. Functional foods that contain bioactive components may provide desirable health benefits beyo...

Vet Med Today: Timely Topics in Nutrition 593 R (Oryza sativa) is one of the most important cereal crops in the world. It is a dietary staple that provides the bulk of daily calories for many companion animals and humans. The bran fraction of rice is a nutrient-rich by-product that has been primarily used as a low-cost feed for livestock and a fiber source in pet food. This review highlights ar...

Cancer cells possess unique metabolic signatures compared to normal cells, including shifts in aerobic glycolysis, glutaminolysis, and de novo biosynthesis of macromolecules. Targeting these changes with agents (drugs and dietary components) has been employed as strategies to reduce the complications associated with tumorigenesis. This paper highlights the ability of several food components to ...

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Various dietary components may modify chronic inflammatory processes at the stage of cytokine production, amplification of nuclear factor-kappaB-mediated inflammatory gene expression, and the release of anti-inflammatory cytokine, transforming growth factor-beta. This review provides a synopsis of the strengths and weaknesses of the evidence that specific bioactive food components influence inf...

Fermented food provides plenty of vital nutrients and bioactive components that affect a number of functions of human body in a positive way. Fermented dairy and food products can be made more functional by incorporating probiotic bacteria such as strains belonging to genera Lactobacillus and Bifidobacterium. A few strains of such food grade bacteria are capable of synthesizing essential biomol...

The discovery of bioactive components in foods is exciting, suggesting the possibility of improved public health through diet. Yet the content of bioactive components in plant food varies, making quality control and intake recommendations problematic. Variation in content of bioactive components in fruits and vegetables depends upon both genetics and environment, including growing conditions, h...