conclusions as a result of the full range uv-vis scanning of the responsible band in the hptlc experiments (200-700 nm), the flavonoid was the most imaginable natural compound. results through the bioassay guided fractionation method, the greatest antibacterial activities were related to the n-hexane extract. it was also revealed that the effective anti-mrsa agent of the assessed plant was a re...

An agar well diffusion bioassay method for determination of clarithromycin in human plasma, using Micrococcus Luteus ATCC 9341 as the assay organism, was compared with a selective high-performance liquid chromatographic (HPLC) method with UV detection. Spiked plasma was used to prepare standard and control samples for both methods. The results of the bioassay analyses with spiked plasma samples...

OBJECTIVES The aim of this work was to develop and validate an HPLC method for gentamicin quantification in different types of biological samples such as animal tissues and cellular material and also in pharmaceuticals. METHODS Poly(lactide-co-glycolide) microparticles (MP) of gentamicin (PLGA 502H MP), THP-1 cells, and plasma and tissue samples of mice treated with the antibiotic either free...

background: crude oil is a very complex composition with harmful effects in human health such as carcinogenesis and blood effects. using the bioassay method to assess the effect of purification process produces useful results. in this study the effect of ozonation to reduce the toxicity of crude oil in the water is investigated. methods: standard sample of the water soluble fraction were prepar...

Regulatory monitoring for most antibiotic residues in edible poultry tissues is often accomplished with accurate, although expensive and technically demanding, chemical analytical techniques. The purpose of this study is to determine if a simple, inexpensive bioassay could detect fluoroquinolone (FQ) residues in chicken muscle above the FDA established tolerance (300 ppb) comparable to a liquid...

A statistical study of fitting log-normal distributions to air sampling concentrations and random intakes is reported in this paper. An improved method on the approximation of a sum of log-normal distributions to a log-normal distribution is used to forecast bioassay results and their uncertainties. These methods can be used in the design and implementation of air control monitoring and bioassa...