According to the World Health Organization, neuropsychiatric diseases account for approximately one third of years lost to disability. Yet, despite this huge disease burden, there is a lack of new treatments under development: approved treatments all essentially target the same target(s), if the target itself is known. There is now considerable evidence for a common set of heritable risk for ps...

Autism spectrum disorders (ASD) are complex neurobio-logical disorders of development characterized by impairments in social interaction and communication, together with restricted, repetitive, and stereotyped interests/behavior. There has been a dramatic increase in the reported rates of ASD over the last 40 years which has risen in USA from 1 in 5000 in the mid-1970s to 1 in 88 in 2012. Howev...