We have developed an inexpensive portable microarray reader that can be applied to standard microscope slide-based arrays and other array formats printed on chemically modified surfaces. Measuring only 19 cm in length, the imaging device is portable and may be applicable to both triage and clinical settings. For multiplexing and adaptability purposes, it can be modified to work with multiple ex...

Utilizing its integrated camera as a spectrometer, we demonstrate the use of a smartphone as the detection instrument for a label-free photonic crystal biosensor. A custom-designed cradle holds the smartphone in fixed alignment with optical components, allowing for accurate and repeatable measurements of shifts in the resonant wavelength of the sensor. Externally provided broadband light incide...

Utilizing its integrated camera as a spectrometer, we demonstrate the use of a smartphone as the detection instrument for a label-free photonic crystal biosensor. A custom-designed cradle holds the smartphone in fixed alignment with optical components, allowing for accurate and repeatable measurements of shifts in the resonant wavelength of the sensor. Externally provided broadband light incide...

A whole-cell bacterial sensor system for short-chain halo-organic acids was constructed, using 2-chloropropionic acid (2-CPA) as a model pollutant. An Escherichia coli host was transformed with a moderate-copy plasmid containing a fusion of two foreign genetic elements: (a) a promoter-containing segment of the Pseudomonas DL-DEX (DL-2-haloacid dehalogenase) encoding gene and (b) bioluminescence...

Cost-effective/sensitive/selective/reliable detectors for firstresponders Point-of-care/clinical applications for pathogen/virus/threat detection and identification Technological challenges for rapid/early/specific sensitive detection Role of nanotechnology and system miniaturization; MEMS and bioMEMS Use of biochip technology; microand nanofluidics Bioinformatics for biodefense Reducing false ...

Highly sensitive, label-free biodetection methods have applications in both the fundamental research and healthcare diagnostics arenas. Therefore, the development of new transduction methods and the improvement of the existing methods will significantly impact these areas. A brief overview of the different types of biosensors and the critical parameters governing their performance will be given...

Cost-effective/sensitive/selective/reliable detectors for firstresponders Point-of-care/clinical applications for pathogen/virus/threat detection and identification Technological challenges for rapid/early/specific sensitive detection Role of nanotechnology and system miniaturization; MEMS and bioMEMS Use of biochip technology; microand nanofluidics Bioinformatics for biodefense Reducing false ...

Ultrasensitive Terahertz Biodetection In article number 2301165, Chao Chang, Xiaohui Du, and co-workers demonstrate a chip-based portable ultra-sensitive THz metasensor by exploring quasi-bound states in the continuum report its capability for sensing low-concentration analytes. The designed is made of split-ring resonator metasurface combining functionalized gold nanoparticles conjugated with ...