Biological images are critical components for a detailed understanding of the structure and functioning of cells and proteins. Image processing and analysis tools increasingly play a significant role in better harvesting this vast amount of data, most of which is currently analyzed manually and qualitatively. A number of image analysis tools have been proposed to automatically extract the image...

We have developed three computer programs for comparisons of protein and DNA sequences. They can be used to search sequence data bases, evaluate similarity scores, and identify periodic structures based on local sequence similarity. The FASTA program is a more sensitive derivative of the FASTP program, which can be used to search protein or DNA sequence data bases and can compare a protein sequ...

The trend in tools for visualization and analysis of cell pathways is to go beyond small-scale static depictions of pathways and towards large-scale networks capturing cellular dynamics. Such tools attempt to construct pathways automatically and integrate data from large datasets in genomics, proteomics and transcriptomics to give a more meaningful representation of cell activity. We look at te...

|The access and exploitation of integrated data repositories and applications is critical for life science. Biologists design protocols that typically rely on complex query pipelines accessing various biological electronic resources (data sources and tools) to consistute data sets for analysis and mining. Integration platforms are needed to allow biologists to acces, manipulate and analyze elec...

UNLABELLED Many tools exist for visually exploring biological networks including well-known examples such as Cytoscape, VisANT, Pathway Studio and Patika. These systems play a key role in the development of integrative biology, systems biology and integrative bioinformatics. The trend in the development of these tools is to go beyond 'static' representations of cellular state, towards a more dy...