54-year-old male patient was admitted in endocrine ward and referred to our hospital for psychiatric consult due to malaise symptoms , dysphoric mood, irritability, insomnia, loss of appetite, increasing the amount of speech, lack of enjoyment of life, hopelessness, thoughts of worthlessness ,thoughts of death (these symptoms was started from 4 months ago ,after some career change ). other symp...

objective: to study the prevalence and demographic characteristics of mood disorders among iranian adults. method: in this cross-sectional population-based epidemiological study (age > 18) in iran, 25180 individuals were selected through a randomized cluster sampling method for a diagnosis using the schedule for affective disorders and schizophrenia (sads). they were then interviewed at home by...

objective: the aim was to determine how personality of major depressive disorder (mdd) patients is different from that of bipolar ii disorder (biid) patients. methods: in this cross-sectional study, two groups of patients with mdd (47 patients) and biid (45 patients) between 18 and 55 years old were included and compared. the research instrument that subjects answered to was temperament and cha...

the molecular mechanisms of the fact that more than 50% of the individuals with the same genetic make up (e.g. identical twins in schizophrenia) do not show the same psychiatric phenotype remained undefined in psychiatry. this along with the failure to find responsible genes with major effects in psychiatric disorders and lack of consistency of genetic association studies led to the current una...

objective: this study aimed to assess deficits of cognitive and emotional aspects of theory of mind in patients with bipolar disorder type 1 within a remission period. methods: in this case- control study, 30 bipolar patients and 30 normal individuals were selected through purposive sampling method for the purpose of the study. then, they were matched based on their educational background and a...

linkage studies and epidemiological findings indicate that some possible genes in schizophrenia (scz) and bipolar mood disorder (bpd) are common. numerous evidences for linkage of two diseases on chromosome 22 have been found. these findings suggest that one or more genes in the 22q11.21 region may be involved in the development of both disorders. in the present case-control study, association ...

objective: this study aimed to evaluate the non-compliance rate in patients with bipolar i disorder (bid). methods: the patients admitted to iran psychiatric hospital who were diagnosed as a case of the first episode mania of bipolar i disorder (dsm-iv-tr) by 2 psychiatrists followed by one of them in a longitudinal, prospective and naturalistic study. in the follow-up early non-compliance/irre...

background: fatty acids play various physiological roles in the organism; they are crucial for the structure of cell membranes, metabolic processes, transmission of nerve impulses and brain functions. in recent years, particular attention has been paid to the rich sources of omega‑3 for the treatment of many diseases, especially mental illnesses. the present study aimed to investigate the effec...

objective: the methylenetetrahydrofolate reductase (mthfr) gene polymorphism c677t is suspected to be a risk factor for psychiatric disorders, but it remains inconclusive whether the mthfr polymorphism c677t is imputed to vulnerability to schizophrenia and bipolar disorder. method: we prompted impetus to appraise this polymorphism in an iranian population. therefore, 90 patients with bipolar di...