Bipolar disorder is characterized by a hypersensitivity to reward-relevant cues and a propensity to experience an excessive increase in approach-related affect, which may be reflected in hypo/manic symptoms. The present study examined the relationship between relative left-frontal electroencephalographic (EEG) activity, a proposed neurophysiological index of approach-system sensitivity and appr...

the present study examined whether negative parenting characteristics are associated with offspring’s bipolar spectrum diagnoses. individuals with bipolar spectrum disorders and matched normal controls completed measures of the parenting behaviors their parents exhibited while the individuals were growing up. lower levels of acceptance/warmth from mothers and higher levels of negative psycholog...

BACKGROUND there is a public health issue regarding the correct diagnosis of BSD: these diseases are often underreferred, underdiagnosed and undertreated/mistreated. To fail to treat BSD may result in serious complications (loss of work, relationship crisis, substance-abuse, suicide, rapes, etc). In order to correctly diagnose Bipolar Spectrum Mood Disorders, it is important to know the patient...

OBJECTIVES Research has found that bipolar spectrum disorders are associated with Behavioral Approach System (BAS) hypersensitivity and both unipolar and bipolar depression are associated with high Behavioral Inhibition System (BIS) sensitivity, but prospective studies of these relationships are lacking. We tested whether BAS and BIS sensitivities prospectively predicted the time to new onsets ...

Background Mounting evidence implicates early life and prenatal immune disturbances in the etiology of severe mental illnesses. Asthma is a common illness associated with chronic aberrant immune responses. We aimed to determine if asthma in childhood and parents is associated with bipolar and schizophrenia spectrum disorders. Methods A cohort study including all children born in Sweden 1973-1...

BACKGROUND Eating disorder (ED) patients often have comorbidities with other psychiatric disorders, especially with mood disorders. Although recent studies suggest an intimate relationship between ED and bipolar disorder (BD), the study on a broader bipolar spectrum definition has not been done in this population. We aimed to study the occurrence of bipolar spectrum (BS) and comorbidities in ea...

A class of bipolar sequences is identified which has optimally flat spectrum using the Complex Reverse Jacket Transform (CRJT). This class is found to correspond exactly to the family of Bent bipolar sequences using the Walsh-Hadamard Transform. In total there are 576 such transforms for which this class has optimal spectrum of which the CRJT is one. The spectral properties of odd-power-of-two ...

BACKGROUND Affective temperaments are presumed to underlie bipolar psychopathology. The TEMPS-A has been widely used to assess affective temperaments in clinical and non-clinical samples. Cross-sectional research supports the association of affective temperaments and mood psychopathology; however, longitudinal research examining risk for the development of bipolar disorders is lacking. The pres...

CONTEXT It has been suggested that patients with major depressive disorder (MDD) who display pretreatment features suggestive of bipolar disorder or bipolar spectrum features might have poorer treatment outcomes. OBJECTIVE To assess the association between bipolar spectrum features and antidepressant treatment outcome in MDD. DESIGN Open treatment followed by sequential randomized controlle...