Start End Topic Speakers 14:00 14:05 Introduction to the Workshop  Sohier Suzy Elneil 14:05 14:25 Neurology of the bladder and the pelvic floor  Thomas Kessler 14:25 14:45 Bladder Symptoms in the Neurological Patient  Xavier Game 14:45 15:05 Pelvic Floor Dysfunction in the Neurological Patient  Alex Digesu 15:05 15:20 Bladder and Pelvic Floor Assement in Neurogenic Bladder and Pelvic Floor ...

Urinary diversion is a detour of the urinary tract. It may be necessary in different scenarios and can either be continent or incontinent, catheterisable or orthotopic. Pathological situations which may demand a urinary diversion are varied and include anatomical, physiological, congenital and traumatic causes, e.g. urethral stenosis and partial or complete urethral disruption; bladder dysfunct...

Type II diabetes is the most prevalent form of diabetes. One of the primary complications of diabetes that significantly affects quality of life is bladder dysfunction. Many studies on diabetic bladder dysfunction have been performed in models of type I diabetes; however, few have been performed in animal models of type II diabetes. Using the Zucker Diabetic Fatty (ZDF) rat model of type II dia...

UNLABELLED The AIM of the study was to validate some of the imaging criteria for voiding dysfunction in children. MATERIAL AND METHODS The study included a number of 55 children with voiding dysfunction symptoms. They were investigated clinically as well as through imaging techniques: renourinary ultrasound, voiding cystourethrography and cystometry. RESULTS The most common symptoms were ur...

Maternal fructose exposure (MFE) programs the development of metabolic syndrome (MetS) in young adult offspring. Epidemiological data indicate that MetS may increase the risks of overactive bladder (OAB) symptoms. However, it remains unknown whether MFE programs MetS-associated bladder dysfunction in adult offspring. Using Sprague-Dawley rats, we investigated the effects of MFE during pregnancy...

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Individuals with functional lower urinary tract disorders including interstitial cystitis (IC)/bladder pain syndrome (BPS) and overactive bladder (OAB) often report symptom (e.g., urinary frequency) worsening due to stress. One member of the transient receptor potential ion channel vanilloid family, TRPV4, has recently been implicated in urinary bladder dysfunction disorders including OAB and I...

Hypothesis / aims of study Nitric oxide (NO) has been recognized as an important neurotransmitter in the lower urinary tract. Previous studies have shown the presence of NO synthases (NOS) in urothelium and detrusor smooth muscle (DSM) in different animal species. Recently, long-term NO blockade has been shown to cause bladder dysfunction and detrusor overactivity in rats [1,2]. However, the me...

Bladder dysfunction is common in Multiple Sclerosis (MS) but little is known of its pathophysiology. We show that mice with experimental autoimmune encephalomyelitis (EAE), a MS model, have micturition dysfunction and altered expression of genes associated with bladder mechanosensory, transduction and signaling systems including pannexin 1 (Panx1) and Gja1 (encoding connexin43, referred to here...

In this overview the influence of functional bladder disturbances and of its treatment on the resolution of vesicoureteral reflux (VUR) in children is discussed. Historically both bladder dysfunction entities, the overactive bladder (OAB) and the dysfunctional voiding (DV), have been described in conjunction with VUR. Treatment of the dysfunction was also considered to influence spontaneous res...