Perioperative dilutional coagulopathy is a major coagulation disorder during adult and pediatric surgery. Although the main underlying mechanisms are comparable, data of the development and management of dilutional coagulopathy in children are scarce. Observational data showed that intraoperative coagulation disorders mainly based on complex disturbances of clot firmness including acquired fibr...

This is the first of two articles describing the uses of point of care testing in coagulation management. The first article describes the basis of thromboelastography with its physical principles and uses. The second describes discussions of case studies in clinical scenarios.

Thromboelastrography (TEG) is one of the most common whole-blood viscoelastic coagulation tests used in clinical laboratories and at the point of care. TEG provides information on coagulation defects that are often difficult to detect using routine laboratory tests such as activated partial prothrombin time or prothrombin time. In certain critically ill patient populations, the use of TEG inste...

The coagulation system undergoes significant change during pregnancy. The clinician caring for the parturient must understand these changes, particularly when the parturient has a pre-existing haematological condition. Because many haematological conditions are rare, there often is limited information to guide the obstetric and anaesthetic management of these parturients.

This corrects the article on p. 505 in vol. 36, PMID: 27578502.

Clinical and experimental observations are described that indicate that intra-articular fibrinogenolysis is a cause of the defect of coagulation seen when blood is extravasated into a synovial joint.