Perfusion refers to the delivery of oxygen and nutrients to tissues by means of blood flow and is one of the most fundamental physiological parameters. Disorders of perfusion also account for most of the leading causes of medical disability and mortality. While measurements of perfusion are of direct diagnostic value in vascular disorders, perfusion measurements also serve as biomarkers for a b...

Background Perfusion imaging visualizes early changes within the ischaemic cascade and has been shown to accurately detect significant coronary artery stenoses. First pass myocardial perfusion CMR yields high spatial resolution and permits quantification of myocardial blood flow. However, perfusion-CMR has only been validated in a small number of previous studies and using relatively early perf...

Abstract Introduction The optimum conditions for normothermic machine perfusion (NMP) in kidney transplantation have yet to be determined. Traditionally, kidneys are perfused with a red blood cell (RBC) based solution at 37°C. NMP subnormothermic temperature without RBCs could reduce the harmful effects of haemolysis but still preserve function. This study examines effect acellular (SNAP) human...

The aim of this work is to analyze quantitative data magnetic resonance ASL-perfusion the liver at admission and follow up patients with viral cirrhosis. study included 34 cirrhosis: 23 (67.6 %) men 11 (32.4 women. All subjects underwent abdominal ultrasound Dopplerography vessels, shear wave elastography, Arterial spin Labeling (ASL) — Perfusion by imaging. Post-processing images was carried o...

Introduction Perfusion is the term applied to capillary blood flow in tissue. Since the blood carries oxygen and nutrition to the tissue through the capillaries, perfusion is important in maintaining tissue viability. The study of brain perfusion has clinical applications due to the changes in perfusion associated with several neurological diseases. Diagnosis, lesion characterisation and follow...

The key to “best practice” rests in understanding that low blood pressure is merely one manifestation of poor perfusion, but it is not the sole finding in shock. Some patients are in shock, despite what appears to be normal blood pressure. Children and young adults are classic examples of patients who do not initially drop their blood pressure when they first fall into shock. Hypotension in adu...

OBJECTIVES/HYPOTHESIS To observe blood perfusion and vascular permeability changes under varying vibration frequency exposures. STUDY DESIGN Animal model. METHODS Blood perfusion was measured using laser Doppler flowmetry in eight rabbit auricular vessels (four rabbits) under nonvibration, and 62.5-Hz/1-mm, 125-Hz/1-mm, and 250-Hz/0.5-mm vibration frequency/amplitude exposures. Another 12 r...

BACKGROUND AND PURPOSE The purpose of this study was to evaluate the potential clinical value of arterial spin-labeled (ASL) perfusion MRI in acute ischemic stroke (AIS) through comparison with dynamic susceptibility contrast (DSC) enhanced perfusion MRI. METHODS Pseudocontinuous ASL with 3-dimensional background-suppressed gradient and spin echo readout was applied with DSC perfusion MRI on ...

Radionuclide studies were performed to determine pulmonary blood flow in six children who had undergone surgery for pulmonary atresia, ventricular septal defect, and hypoplastic pulmonary arteries with or without major aortopulmonary collateral arteries. Lung blood flow was assessed from both particle perfusion lung scans and the pulmonary and systemic phase of a radionuclide dynamic flow study...

This paper presents an unified algorithm that enables detection of lesions in cerebral blood flow (CBF), cerebral blood volume (CBV) and time to peek (TTP) perfusion maps. The algorithm has one adaptive parameter for each type of perfusion map, the rest of algorithm is common for all kinds of perfusion images. There are two steps of the algorithm: in the first step the algorithm detects symmetr...