Segmentation of retinal blood vessels is significant to diagnosis and evaluation of ocular diseases like glaucoma and systemic diseases such as diabetes and hypertension. The retinal blood vessel segmentation for small and low contrast vessels is still a challenging problem. To solve this problem, a new method based on cake filter is proposed. Firstly, a quadrature filter band called cake filte...

A wide variety of ocular diseases are associated with abnormalities in ocular circulation. As such, there is considerable interest in techniques for quantifying retinal blood flow, among which Doppler optical coherence tomography (OCT) may be the most promising. We present an approach to measure retinal blood flow in the rat using a new optical system that combines the measurement of blood flow...

AIMS Proper blood vessel formation is essential in health and is often dysregulated in ischaemic diseases. Therefore, regulatory mechanisms that control angiogenesis and arteriogenesis are required to improve treatment of ischaemic diseases. The aim of this study was to investigate the role of homeobox transcription factor HoxB5 overexpression during revascularization in ischaemic disease. ME...

Estimation of the geometric parameters of blood vessels is an important stage in the diagnosis of many cardiovascular diseases. In this work, we describe a method for estimating the diameter of blood vessels based on a modified local fan transform. We present experimental results that show in which way the accuracy of blood vessel estimation is affected by the noise-to-signal ratio in the image...

VEGFs (vascular endothelial growth factors) are master regulators of vascular development and of blood and lymphatic vessel function during health and disease in adults. This family of five mammalian ligands acts through three RTKs (receptor tyrosine kinases). In addition, co-receptors such as NRPs (neuropilins) associate with the ligand-receptor signalling complex and modulate the output. Ther...

In recent days glaucoma related problems are tremendously increased in a stratergical manner. Hence it is to be considered as a serious threat in biomedical problem among human beings. proper arrangement of retinal vessel provides information about the retinal abnormalities. This process help to find cause several retinal diseases. The assessment of blood vessel is used to find eye diseases suc...

Abstract Numerical simulations for blood flows related to cardiovascular diseases are presented. Differences in vessel morphologies produce different flow characteristics, stress distributions, and ultimately outcomes. Some examples illustrating the effects of curvature torsion on presented both simplified patient-specific simulations. The goal this study is understand relationships between geo...

Many diseases affect blood vessel morphology. This report analyzes vessel attributes (tortuosity, vessel density, radius, and terminal branch count) within 5 malignant gliomas as seen by high-resolution MR. Results are compared to those in the same anatomical region of 14 normal controls. All tumor patients had marked increases in vessel tortuosity and terminal branch count. These results raise...

Automatic segmentation of blood vessels in fundus images is of great importance as eye diseases as well as some systemic diseases cause observable pathologic modifications. It is a binary classification problem: for each pixel we consider two possible classes (vessel or non-vessel). We use a GPU implementation of deep max-pooling convolutional neural networks to segment blood vessels. We test o...