نتایج جستجو برای: bloodbrain barrier permeability
تعداد نتایج: 133084 فیلتر نتایج به سال:
barrier properties are one of the most important factors in the edible film. in this study, edible mungbean films were prepared containing (0%, 15%, 30%, 45%) concentrations of rosemary aqueous extract. then the effect of rosemary was investigated on colorimetric and barrier properties (water vapor permeability, oxygen permeability). rosemary extract increased the absorption of color in the vis...
Stereospecific Permeability of Rat BloodBrain Barrier to Lactic Acid • Blood and whole brain C and P activities were determined in hepatectomized rats one, two, five and ten minutes after intravenous (I.V.) injection of C-labeled L-lactate or D-lactate and P-labeled rat red blood cells. Whole brain homogenate C was corrected for blood "C and chemically partitioned into "C-lactate, CO2 and other...
conclusion the minimum concentration of triolein emulsion required to increase vascular permeability adequately with minimal brain edema in a cat model was 0.5%. results the lesion hemispheres showed mild hyperintensity due to edema on t2-weighted images, and contrast enhancement on post-contrast t1-weighted images in cats of group 1-5. cers showed statistically significant differences between ...
Background and Objective: Recent studies suggest that sub-lethal ischemia protect the brain from subsequent ischemic injuries. This study was an effort to identify and shed light on the nature of changes in the blood brain barrier permeability and brain edema. Materials and Methods: Rats were divided into four main experimental groups, each of 21 animals. The first group acted as a model of isc...
It has been stated that hypercapnia increases the permeability of the bloodbrain barrier to several compounds, e.g., trypan blue,' sulphate2 and iodinated serum albumin."' The experiments just cited have shown that during hypercapnia more of the substance under study has passed from blood into the brain tissue than in control animals, but such an effect could have been due to the expansion of t...
Background Multiple sclerosis (MS) is an autoimmune disease of central nervous system, which unknown etiology, but recent studies suggest important role of oxidative stress in its pathogenesis. The aim of our study was to analyze various markers of oxidative and nitrative damage, their mutual correlations and correlations with the state of the bloodbrain barrier (BBB) in multiple sclerosis pati...
Effect of Deferoxamine on Blood-brain Barrier Disturbances following Subarachnoid Haemorrage in Cats
Disruption of the blood brain barrier plays a significant role in the pathophysiology of subarachnoid haemorrhage. Experimental studies concerning subarachnoid haemorrhage suggested the primary role of free radicals and subsequently lipid peroxidation in the pathogenesis of vasospasm. In this experimental study the role of deferoxamine on blood brain barrier disturbance in vasospasm was evaluat...
Although the central nervous system (CNS) is separated from the immune system by bloodbrain barrier and traditionally considered “immune priviledged”, our immune cells are capable of targeting the brain, leading to the development of CNS autoimmune disorders. Multiple sclerosis (MS) is one such autoimmune disorder of the CNS in which myelin components are particularly targeted by the immune sys...
abstract ischemic brain edema is one of the most important complications of a stroke. this study aims to investigate the impact of pre-feeding of flax seed oil on blood-brain barrier in rat stroke model. in this experimental study animals were randomly divided into 3 groups of experiment, sham, and control. each testing group itself was consisted of 3 subgroups receiving doses of flaxseed oil w...
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