OBJECTIVE To assess the efficacy of a chlorhexidine-impregnated dressing for prevention of central venous catheter-related colonization and catheter-related bloodstream infection using meta-analysis. DATA SOURCES Multiple computerized database searches supplemented by manual searches including relevant conference proceedings. STUDY SELECTION Randomized controlled trials evaluating the effic...

BACKGROUND Polymicrobial infections in adults and children are associated with increase in mortality, duration of intensive care and healthcare costs. Very few studies have characterized polymicrobial bloodstream infections in the neonatal unit. Considerable variation has been reported in incidence of polymicrobial infections and associated clinical outcomes. We characterized the risk factors a...

BACKGROUND Information from blood cultures is utilized for infection control, public health surveillance, and clinical outcome research. This information can be enriched by physicians' assessments of positive blood cultures, which are, however, often available from selected patient groups or pathogens only. The aim of this work was to determine whether patients with positive blood cultures can ...

OBJECTIVES To examine the effectiveness of antimicrobial-impregnated and heparin-bonded catheters relative to standard central venous catheters in lessening catheter-related bloodstream infections. DATA SOURCES Articles were identified by computer-assisted searching. STUDY SELECTION Studies were eliminated from further consideration if they did not contain original data relevant to lessenin...

Abstract Background There is evidence that bacterial co-infection in respiratory viruses leads to morbidity and mortality. Patients with decreased immunity are prone co-infection. A lack of judicious use antibiotics the spread multi-drug resistant bacteria (MDR) have a long-term negative impact. In this study, we attempted observe pattern antibacterial its impact on secondary infection. Methods...

BACKGROUND AND OBJECTIVES Elderly patients require tunneled central vein dialysis catheters more often than younger patients. Little is known about the risk of catheter-related bloodstream infection in this population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This study identified 464 patients on hemodialysis with tunneled central vein dialysis catheters between 2005 and 2007 and exclude...

Nosocomial bloodstream infections are a leading cause of death in the United States. If we assume a nosocomial infection rate of 5%, of which 10% are bloodstream infections, and an attributable mortality rate of 15%, bloodstream infections would represent the eighth leading cause of death in the United States. Because most risk factors for dying after bacteremia or fungemia may not be changeabl...