Pneumococcal bacteriocins (pneumocins) are antibacterial toxins that mediate intra-species competition within the human host. However, the triggers of pneumocin expression are poorly understood. Using RNA-sequencing, we mapped the regulon of the pneumocin cluster (blp) of Streptococcus pneumoniae D39. Furthermore, by analogy with pneumococcal competence, we show that several antibiotics activat...

The cell membrane-associated enzyme CD10/neutral endopeptidase 24.11 (CD10/NEP) functions in multiple organ systems to downregulate responses to peptide hormones. Recently, CD10/NEP was found to hydrolyze bombesin-like peptides (BLP), which are mitogens for normal bronchial epithelial cells and small cell lung carcinomas. Growth of BLP-responsive small cell lung carcinomas was potentiated by CD...

Specifically, suppose we have a BLP model which consists Currently most computer security models are classified among the tl:l~ types; access control, information flow, and non-interference. Within the realm of access control lies the classical Bell-LaPadula model. A BLP model consists of a set of subjects and objects, thr~e security level functions, and a discretionary access matrix together w...

We examined fluctuations in band-limited power (BLP) of local field potential (LFP) signals recorded from multiple electrodes in visual cortex of the monkey during different behavioral states. We asked whether such signals demonstrated coherent fluctuations over time-scales of seconds and minutes, and would thus serve as good candidates for direct comparison with data obtained from functional m...

All bacteria contain proteins in which their amino-terminal cysteine residue is modified with N-acyl S-diacylglycerol functions, and peptides and proteins bearing this modification are immunomodulatory. The major outer membrane lipoprotein of Escherichia coli, the Braun lipoprotein (BLP), is the prototypical triacylated cysteinyl-modified protein. We find it is as active as LPS in stimulating h...

Belief Logic Programming (BLP) is a novel form of quantitative logic programming in the presence of uncertain and inconsistent information, which was designed to be able to combine and correlate evidence obtained from non-independent information sources. BLP has non-monotonic semantics based on the concepts of belief combination functions and is inspired by Dempster-Shafer theory of evidence. M...

An alternative definition of the linear bilevel programming problem BLP has recently been proposed by Lu, Shi, and Zhang. This note shows that the proposed definition is a restriction of BLP . Indeed, the new definition is equivalent to transferring the first-level constraints involving second-level variables into the second level, resulting in a special case of BLP in which there are no first-...

The structures and hemolytic and bactericidal activities of three bombinin-like peptides, or BLP-1-3, from the skin of Bombina orientalis are described. The peptides were isolated from the skin of B. orientalis and sequenced by tandem mass spectrometry and are amphipathic, cationic peptides of 25-27 amino acids in length. The sequence of the most abundant member (BLP-1) is: Gly-Ile-Gly-Ala-Ser-...