Composite Binary Offset Carrier (CBOC) modulation is currently proposed for future Open Service (OS) Galileo signals in E1 frequency band. CBOC consists of a weighted sum or difference of two sine Binary Offset Carrier (BOC) waveforms: a sine BOC(1,1) and a sine BOC(6,1) component. The transmitted OS signal has both data and pilot channels. Data and pilot channels use slightly different modulat...

OBJECTIVE To demonstrate the application of an approach for assessing efficiency and rationality in the use of resources for the care of patients with AIDS (PWA), using data for north-east Italy. DESIGN An economic methodology, the balance of care (BoC) approach, enabled identification of scenarios for the current, planned and recommended provision of care in the study region. METHODS Data ...

During development of the embryonic zebrafish brain, the differential expression of axon guidance molecules directs the growth of axons along defined neuronal tracts. Neurons within the dorsorostral cluster of the presumptive telencephalon project axons ventrally along the supraoptic tract. Brother of Cdo (Boc) is a known axon guidance molecule that is expressed in a broad band lying ventral to...

Background: Achievement of early viral suppression is important in patients with chronic HCV infection treated with telaprevir (TLV) or boceprevir (BOC) to avoid selection of drug resistance and attain cure. No head-to-head studies comparing TLV and BOC have been performed so far. Methods: All consecutive individuals who initiated triple HCV therapy with TLV or BOC outside clinical trials at th...

Peptides patterned on the N-terminal sequence of fibronectin were synthesized and tested for amine acceptor qualities in reactions with dansylcadaverine catalyzed either by coagulation factor XIIIa or intracellular transglutaminase (protein-glutamine:amine gamma-glutamyltransferase, EC 2.3.2.13). On the basis of inverse half-saturations of the enzymes, the order of acceptor substrate affinity f...

Synthetic caspase inhibitors and particularly broad-spectrum caspase inhibitors can prevent cells from death or at least slow down cell death process and abrogate some apoptotic hallmarks [Kitanaka, C., Kuchino, Y., 1999. Caspase-independent programmed cell death with necrotic morphology. Cell Death and Differentiation 6, 508-515]. However, not all synthetic caspase inhibitors diminish cell dea...

Kinetic resolution of 2-arylindolines (2,3-dihydroindoles) was achieved by treatment their N-tert-butoxycarbonyl (Boc) derivatives with n-butyllithium and sparteine in toluene at −78 °C followed electrophilic quench. The unreacted starting materials together the 2,2-disubstituted products could be isolated high enantiomer ratios. Variable temperature NMR spectroscopy showed that rate Boc rotati...

Binary offset carrier (BOC) describes a class of spread-spectrum modulations recently introduced for the next generation of global navigation satellite systems (GNSSs). The design strategies of these BOC signals have so far focused on the spectral properties of these signals. In this paper, we present a time-domain fingerprint for each BOC signal given by a unique histogram of counted time elap...

The multipath effect is one of the main error sources in the Global Satellite Navigation Systems (GNSSs). The code correlation reference waveform (CCRW) technique is an effective multipath mitigation algorithm for the binary phase shift keying (BPSK) signal. However, it encounters the false lock problem in code tracking, when applied to the binary offset carrier (BOC) signals. A least-squares a...

The binary offset carrier (BOC) proposed for the global navigation satellite systems (GNSS) will enhance navigation performance and spectrum compatibility. However, the acquisition process is made more complex, due to the ambiguity in the autocorrelation function (ACF) of BOC. This paper proposes an unambiguous acquisition technique for the new cosine phased BOC (cosine-BOC) modulated signals, ...