Ajaxon, I. 2017. Can Bone Void Fillers Carry Load? Behaviour of Calcium Phosphate Cements Under Different Loading Scenarios. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1492. 67 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9865-8. Calcium phosphate cements (CPCs) are used as bone void fillers and as complements to hardware ...

In early 1980s, researchers discovered self-setting calcium orthophosphate cements, which are a bioactive and biodegradable grafting material in the form of a powder and a liquid. Both phases after mixing form a viscous paste that after being implanted sets and hardens within the body as either a non-stoichiometric calcium deficient hydroxyapatite (CDHA) or brushite, sometimes blended with un-r...

INTRODUCTION: Synthetic calcium phosphate cements (CPC) which mimic the chemical structure of the mineral composition of bone have been well accepted as bone grafting materials due to their consistent osteoconductivity, ease of use, and mechanical properties but are limited in application due to their lack of osteoinductive potential. Demineralized Bone Matrix (DBM) has also found significant a...

Composite bone cements were formulated with bioactive glass (MgO--SiO(2)--3CaO. P(2)O(5)) as the filler and hydrophilic matrix. The matrix was composed of a starch/cellulose acetate blend (SCA) as the solid component and a mixture of methylmethacrylate/acrylic acid (MMA/AA) as the liquid component. The curing parameters, mechanical properties, and bioactive behavior of these composite cements w...

We performed a randomised, radiostereometric study comparing two different bone cements, one of which has been sparsely clinically documented. Randomisation of 60 total hip replacements (57 patients) into two groups of 30 was undertaken. All the patients were operated on using a cemented Charnley total hip replacement, the only difference between groups being the bone cement used to secure the ...

In early 1980s, researchers discovered self-setting calcium orthophosphate cements, which are a bioactive and biodegradable grafting material in the form of a powder and a liquid. Both phases form after mixing a viscous paste that after being implanted, sets and hardens within the body as either a non-stoichiometric calcium deficient hydroxyapatite (CDHA) or brushite, sometimes blended with unr...

The use of polymethylmethacrylate (PMMA) cement to reinforce fragile or broken vertebral bodies (vertebroplasty) leads to extensive bone stiffening. This might be one reason for fractures at the adjacent vertebrae following this procedure. PMMA with a reduced Young's modulus may be more suitable. The goal of this study was to produce and characterize PMMA bone cements with a reduced Young's mod...

Bone cements produced by different manufacturers vary in their mechanical properties and antibiotic elution characteristics. Small changes in the formulation of a bone cement, which may not be apparent to surgeons, can also affect these properties. The supplier of Palacos bone cement with added gentamicin changed in 2005. We carried out a study to examine the mechanical characteristics and anti...

Introduction: Before new products are released on the orthopaedic market they should be analyzed at a pre-clinical stage and tested in restricted clinical trials [1]. That this process is not always adequately followed is demonstrated by unacceptable clinical results with some products which had to be withdrawn from the orthopaedic market [2,3]. In this study we assessed the creep properties of...