BACKGROUND Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT) has been translated from English into several languages. Currently, there is no validated translation of FACT-BMT in Arabic. Here, we are reporting the first Arabic translation and validation of the FACT-BMT. METHODS The study was approved by the Institutional Research Advisory Council. The Arabic translation...

Improving survival rates following pediatric bone marrow transplantation (BMT) will likely result in greater numbers of children progressing to end-stage renal disease (ESRD) because of prior chemotherapy, irradiation, sepsis, and exposure to nephrotoxic agents. Renal transplantation remains the treatment of choice for ESRD; however, the safety of renal transplantation in this unique population...

We used the polymerase chain reaction (PCR) to detect residual leukemia-specific mRNA in blood and marrow from 37 patients in complete hematologic and cytogenetic remission after allogeneic bone marrow transplant (BMT) for chronic myeloid leukemia (CML). Our two-step PCR method involved the use of "nested primers" in the second step and could detect one K562 cell diluted into 10(5) normal cells...

Infection is a common problem for bone marrow transplant (BMT) recipients during the period of neutropenia that immediately follows the procedure. Gram-negative infections present a particular hazard in these immunocompromised hosts. To augment host defenses against one such pathogen, Pseudomonas aeruginosa, we immunized bone marrow transplant donors and/or recipients with a polyvalent 0-polysa...

background: chronic graft versus host disease (cgvhd) is one of the most serious potential complications of allogeneic bone marrow transplantation. study design and method: we analyzed the incidence of cgvhd and its associated risk factors in a group of 161 iranian recipients of hla-identical sibling transplants, with at least 90 days post-transplantation survival. in the majority of cases (n=7...

Bone marrow transplantation (BMT) has become an accepted form of therapy for the treatment of a broad range of haematological, immunological, and inherited metabolic diseases. ~-4 In many cases it offers the opportunity for cure in previously incurable disease states. Examples include refractory leukaemias, aplastic anaemia, primary immunodeficiency syndromes, several inborn errors of metabolis...

When successful, human leukocyte antigen (HLA)-matched bone marrow transplantation with reduced-intensity conditioning is a cure for several nonmalignant hematologic disorders that require chronic transfusion, such as sickle cell disease and aplastic anemia. However, there are unusually high bone marrow transplant (BMT) rejection rates in these patients. Rejection correlates with the number of ...

Infection is a common problem for bone marrow transplant (BMT) recipients during the period of neutropenia that immediately follows the procedure. Gram-negative infections present a particular hazard in these immunocompromised hosts. To augment host defenses against one such pathogen, Pseudomonas aeruginosa, we immunized bone marrow transplant donors and/or recipients with a polyvalent O-polysa...

Background: Despite close monitoring of transplant patients, cytomegalovirus (CMV) infection remains one of the most critical problems in the field of transplantation. This study aims to investigate the relationship between CMV viral load and clinical laboratory findings in transplant recipients. Materials And Methods: Thirty-four transplant recipients comprising 15 kidney transplant (KT) reci...

Human herpesvirus 6 (HHV-6) infection was studied in 82 bone marrow transplant (BMT) recipients (72 allogeneic, 10 autologous). All recipients and 30 donors were seropositive for HHV-6 antibody at the time of bone marrow transplantation. Thirty-one recipients (37.8%) had HHV-6 viremia 2-4 weeks after transplantation. The incidence of HHV-6 viremia was significantly higher among allogeneic BMT r...