OBJECTIVES To evaluate the extent of bone fill over 3 years following the surgical treatment of peri-implantitis with bone grafting with or without a membrane. MATERIAL AND METHODS In a non-submerged wound-healing mode, 15 subjects with 27 implants were treated with a bone substitute (Algipore(®)) alone and 17 subjects with 29 implants were treated with the bone substitute and a resorbable me...

PURPOSE The aim of this study was to determine the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2)-loaded synthetic bone substitute on implants that were simultaneously placed with sinus augmentation in rabbits. METHODS In this study, a circular access window was prepared in the maxillary sinus of rabbits (n=5) for a bone graft around an implant (Ø 3×6 mm) that was simultan...

PURPOSE The aim of this study was to evaluate the improvement of osteogenic potential of biphasic calcium phosphate (BCP) bone substitute coated with synthetic cell-binding peptide sequences in a standardized rabbit sinus model. METHODS Standardized 6-mm diameter defects were created bilaterally on the maxillary sinus of ten male New Zealand white rabbits, receiving BCP bone substitute coated...

statement of problem: reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. platelet-rich plasma (prp) offers a new and potentially useful adjunct to bone substitute materials (e.g. xenografts) in oral and maxillofacial bone and implant reconstructive surgery. purpose: an animal study was carried out to investigate the influence of prp ...

introduction : deproteinized bovine bone mineral (bio-oss) is a xenogenic bone substitute, widely used in maxillofacial bone regeneration. the aim of this in vitro study was to investigate its influence on the growth behavior of human osteosarcoma cell line, saos-2 culture, and compare it with the physiologic dose of dexamethasone, an inductive factor for osteoblasts. materials and methods: hum...