Bovine ephemeral fever virus (BEFV) is an arthropod-borne rhabdovirus that causes a debilitating disease of cattle in Africa, Asia, and Australia; however, its global geodynamics are poorly understood. An evolutionary analysis of G gene (envelope glycoprotein) ectodomain sequences of 97 BEFV isolates collected from Australia during 1956 to 2012 revealed that all have a single common ancestor an...

BACKGROUND The bovine ephemeral fever virus (BEFV) glycoprotein neutralization site 1 (also referred as G1 protein), is a critical protein responsible for virus infectivity and eliciting immune-protection, however, binding peptides of BEFV G1 protein are still unclear. Thus, the aim of the present study was to screen specific polypeptides, which bind BEFV G1 protein with high-affinity and inhib...

Akabane and bovine ephemeral fever (BEF) viruses cause vector-borne diseases. In this study, inactivated Akabane virus (AKAV)+Bovine ephemeral fever virus (BEFV) vaccines with or without recombinant vibrio flagellin (revibFlaB) protein were expressed in a baculovirus expression system to measure their safety and immunogenicity. Blood was collected from mice, guinea pigs, sows, and cattle that h...

In September 2012, several cows and a calf showed decreased activity, anorexia and fever on Ishigaki Island, Okinawa Prefecture, Japan, and the cases were diagnosed as bovine ephemeral fever (BEF). We isolated BEF virus (BEFV) from one of the affected cows and then determined the complete genome sequence of the G gene, which encodes a class I transmembrane glycoprotein of BEFV. The BEFV isolate...

introduction bovine ephemeral fever (bef) is an arthropod-borne viral disease of cattle and water buffalo, spanning tropical and subtropical zones in asia, australia, and africa continents. the clinical signs of bef disease in cattle are acute febrile reaction, stiffness, lameness, depression, cessation of rumination, and constipation. this disease was caused by ephemerovirus of the rhabdovirid...

Arboviruses (arthropod-borne viruses) are a group of pathogens that are transmitted by hematophagous arthropods, mainly mosquitoes and ticks, between susceptible vertebrates [1]; many of them are also characterized by their movement through arthropod communi‐ ties: vertical (or transovarial) [2] and venereal transmission [3]. Thus far, more than 500 ar‐ boviruses have been identified worldwide,...