In the report, “Notes from the Field: Lead Poisoning in an Infant Associated with a Metal Bracelet — Connecticut, 2016” on page 916, the second paragraph should have read “The parents reported that the child intermittently wore a handmade “homeopathic magnetic hematite healing bracelet” that they had purchased from an artisan at a local fair (Figure). The bracelet was described as “homeopathic,...

In the report, “Notes from the Field: Lead Poisoning in an Infant Associated with a Metal Bracelet — Connecticut, 2016” on page 916, the second paragraph should have read “The parents reported that the child intermittently wore a handmade “homeopathic magnetic hematite healing bracelet” that they had purchased from an artisan at a local fair (Figure). The bracelet was described as “homeopathic,...

background :    searching for the potent natural antibiotics will improve the treatment of most infectious diseases. cyclotides are potent active peptides derived from some plant families like violaceae. viola tricolor (the pansy) has been found to have numerous cyclotides. nowadays cyclotides attract more attention for their antibacterial activities.  the current research studied the antimicro...

Cyclotides are ultrastable plant proteins characterized by the presence of a cyclic amide backbone and three disulfide bonds that form a cystine knot. Because of their extreme stability, there has been significant interest in developing these molecules as a drug design scaffold. For this potential to be realized, efficient methods for the synthesis and oxidative folding of cyclotides need to be...

Cyclotides are macrocyclic knotted peptides originating from plants. They are extremely stable and have a range of bioactivities including anti-HIV and insecticidal activity. Given the stability of the cyclotide framework, there is interest in using these peptides as scaffolds in drug design. In the current study, we have shown that nano-LC Fourier transform mass spectrometry (FTMS) is an effec...

OBJECTIVE To evaluate whether hospitalised patients would agree to wear an identification bracelet and whether patient acceptability is improved by more detailed explanations or by using a code instead of a name on the bracelet. DESIGN Patient survey that tested two variables in a randomised factorial design. Explanations about identification bracelets were given (a) with or without examples ...

Cyclotides are a family of plant proteins that are characterized by a cyclic backbone and a knotted disulfide topology. Their cyclic cystine knot (CCK) motif makes them exceptionally resistant to thermal, chemical, and enzymatic degradation. By disrupting cell membranes, the cyclotides function as host defense peptides by exhibiting insecticidal, anthelmintic, antifouling, and molluscicidal act...

Cyclotides are peptides from plants of the Rubiaceae and Violaceae families that have the unusual characteristic of a macrocylic backbone. They are further characterized by their incorporation of a cystine knot in which two disulfides, along with the intervening backbone residues, form a ring through which a third disulfide is threaded. The cyclotides have been found in every Violaceae species ...

Athletes are constantly searching for something that will give them a competitive edge. Performance jewelry is one of the latest products on the market designed to improve athletic performance. The most common claims are that wearing this performance jewelry will improve flexibility, balance, and strength. There is considerable marketing of these products, including testimonial evidence by high...

Cyclotides are plant mini-proteins whose natural function is thought to be to protect plants from pest or pathogens, particularly insect pests. They are approximately 30 amino acids in size and are characterized by a cyclic peptide backbone and a cystine knot arrangement of three conserved disulfide bonds. This article provides an overview of the reported pesticidal or toxic activities of cyclo...