Background: Stroke is the third leading cause of invalidism and death in industrialized countries. There are conflicting reports about the effects of Angiotensin II on ischemia-reperfusion brain injuries and most data have come from chronic hypertensive rats. In this study, hypotensive and non-hypotensive doses of candesartan were used to investigate the effects of angiotensin II AT1 receptor b...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : traumatic brain injury (tbi) is known as one of the most important causes of mortality in middle-aged population. the aim of this study was to evaluate the effects of gabapentin in improvement of consciousness level in these patients. methods : this randomized clinical trial was performed in march 2008 to sept...

A traumatic brain injury (TBI) is an that disrupts the normal function, and caused by a bump, blow, or jolt to head penetrating injury. TBI range from mild concussions, without loss of consciousness, severe TBI, which can result in deep coma death. Types TBI's patients sustain include hematomas, CTE. The length time have symptoms depends on severity, with lasting few days even rest patient’s li...

OBJECTIVE Many troops deployed in Iraq and Afghanistan have sustained blast-related, closed-head injuries from being within non-lethal distance of detonated explosive devices. Little is known, however, about the mechanisms associated with blast exposure that give rise to traumatic brain injury (TBI). This study attempts to identify the precise conditions of focused stress wave energy within the...

Injury statistics have found the most common accident situation to be an oblique impact. An oblique impact will give rise to both linear and rotational head kinematics. The human brain is most sensitive to rotational motion. The bulk modulus of brain tissue is roughly five to six orders of magnitude larger than the shear modulus so that for a given impact it tends to deform predominantly in she...

The complex pathophysiologic phenomena encountered in patients with traumatic brain injuries can be viewed, ultimately, as the brain ’ s response to an external mechanical force. Preventing and treating the consequences of these injuries require an understanding of the mechanical factors that induce the injuries. In this chapter, we focus on the acute consequences of traumatic loading, referred...

a motor vehicle seat belt use law for the driver and front-seat passenger was implemented in taiwan on june 1, 2001. the purpose of this study was to determine the effect of motor vehicle seat belt use on the severity of traumatic brain injuries because of motor vehicle accidents.data were collected from 27 major teaching hospitals four years before june 1, 2001 and until may 31, 2013. a total ...