Abnormal variations of the neonatal brain perfusion can result in long-term neurodevelopmental consequences and cerebral imaging play an important role diagnostic therapeutic decision-making. To identify at-risk situations, must accurately evaluate both regional global perfusion. date, assessment remains challenging. The available modalities such as magnetic resonance (MRI), ultrasound imaging,...

BACKGROUND AND PURPOSE Low brain tissue perfusion due to abnormal venous drainage is thought to be a central mechanism of brain damage in SWS. Here, HR-PWI was used to quantify WM perfusion abnormalities and to correlate these with brain atrophy and clinical variables. MATERIALS AND METHODS Fourteen children (age range, 0.8-10.0 years) with unilateral SWS underwent MR imaging examinations, in...

Background: The assessment of brain death can be challenging in critically ill patients, and cerebral perfusion quantification might give information on the brain tissue viability. Intravoxel incoherent motion perfusion imaging is a magnetic resonance imaging technique, which extracts perfusion information from a diffusion-weighted sequence, and provides local, microvascular perfusion assessmen...

1. Introduction An important feature of brain perfusion is that it can adjust itself based on tissue demand and others conditions. This property is to some extent more clinically relevant compared to baseline perfusion only, because deficits in many brain disorders are often most pronounced when the brain is asked to perform a demanding task. Therefore, perfusion techniques are sometimes used i...

The development of cognitive function in children has been related to a regional metabolic increase and an increase in regional brain perfusion. Moreover, brain perfusion plays an important role in the pathogenesis of brain damage in high-risk neonates, both preterm and full-term asphyxiated infants. In this article, we will review and discuss several existing imaging techniques for assessing n...

The intravoxel incoherent motion (IVIM) model allows to map diffusion (D) and perfusion-related parameters (F D*). Parameter estimation is, however, error-prone due the non-linearity of signal model, limited signal-to-noise ratio (SNR) small volume fraction perfusion in in-vivo brain. In present work, performance Bayesian inference was examined presence brain pathologies characterized by hypo- ...

BACKGROUND It is well established that aging and vascular processes interact to disrupt cerebral hemodynamics in older adults. However, the independent effects of cerebral perfusion on neurocognitive function among older adults remain poorly understood. We examined the associations among cerebral perfusion, cognitive function, and brain structure in older adults with varying degrees of vascular...

We measured brain tissue Po2 in the frontal and occipital cortices, mid-brain and basal ganglia in monkeys for up to 5 hours after 16 min global brain ischemia to gain some insight into those factors responsible for the selective vulnerability of the brain to ischemic anoxia. Brain tissue Po2 measurements were made with gold microelectrodes with tip diameters of 5 to 10 nm. Reoxygenation of the...

Post stroke dementia is one of the most common complications of stroke that is preventable and relatively treatable too. The purpose of the study is comparison between the positive findings in brain CT scan and brain perfusion SPECT. 15 patients who were complicated by dementia after cerebrovascular accident and also 5 patients as a control group enrolled in this study. Brain CT scan and ...