background: boric acid (ba) is commonly used as pesticide, disinfectant and wood preservative. its ingestion can cause serious organ damages resulting in death. case report: a 19 year old man was found dead with two empty packs of ba tablets in vicinity of his body. on autopsy examination, brownish stains along with right angle of mouth and right nostril were found. stomach was damaged with hem...

Multiple Sclerosis (MS) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. In this study for evaluation effect of mercuric on progression of MS we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model of MS in C57BL/6 mi...

Multiple Sclerosis (MS) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. In this study for evaluation effect of mercuric on progression of MS we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (EAE) model of MS in C57BL/6 mi...

multiple sclerosis (ms) is a neurodegenerative and autoimmune disease that it’s molecular etiology and factors involving in its progression remains unknown. in this study for evaluation effect of mercuric on progression of ms we investigated the additive effect of mercuric sulfide on the brain mitochondrial dysfunction in experimental autoimmune encephalomyelitis (eae) model of ms in c57bl/6 mi...

The blood-brain barrier restricts the administration of drugs for neurological diseases. K16ApoE is an effective drug delivery carrier to deliver across barrier, but it contains acute and high toxicity. toxicity mechanism must be revealed clinical uses. Previous studies hypothesized that was acetylcholinesterase inhibition in brain. However, these used improper buffers AChE assay, further leadi...

Background: Boric acid (BA) is commonly used as pesticide, disinfectant and wood preservative. Its ingestion can cause serious organ damages resulting in death. Case report: A 19 year old man was found dead with two empty packs of BA tablets in vicinity of his body. On autopsy examination, brownish stains along with right angle of mouth and right nostril were found. Stomach was damaged with hem...