Deranged protein metabolism is known to complicate uremia. Insulin resistance is evident in chronic hemodialysis (CHD) patients. We hypothesized that the degree of insulin resistance would predict protein catabolism in non-diabetic CHD patients. We examined the relationship between Homeostasis Model Assessment (HOMA) and fasting whole-body and skeletal muscle protein turnover in 18 non-diabetic...

We investigated the effect of insulin administered as part of a hyperinsulinemic-normoglycemic clamp on protein metabolism after coronary artery bypass grafting (CABG) surgery. Eighteen patients were studied, with nine patients in the control group receiving standard metabolic care and nine patients receiving insulin (5 mU·kg(-1)·min(-1)). Whole body glucose production, protein breakdown, synth...

Protein balance in rat muscles incubated in vitro is influenced by the supply of insulin, leucine and various hormones at physiological concentrations (0.1-0.5 mM) (Goldberg & Chang, 1978; Goldberg et al., 1980). Leucine, but no other amino acid, stimulates protein synthesis and inhibits protein breakdown in this tissue. Metabolism of leucine is necessary for its inhibitory effect on proteolysi...

1. We have investigated the effects of moderate long-term exercise on protein turnover in fed man by measuring the extent of whole-body nitrogen production, the labelling of urinary ammonia from ingested [15N]glycine and plasma, muscle and urine free amino acid concentrations. 2. Judged both from nitrogen production, and from the extent of 13CO2 production from ingested L-[1-13C]leucine, exerci...

26 In healthy individuals post-exercise protein supplementation increases muscle protein anabolism. 27 In patients with muscular dystrophies, aerobic exercise improves muscle function, but the effect of 28 exercise on muscle protein balance is unknown. 29 Therefore, we investigated 1) muscle protein balance before, during, and after exercise and 2) the 30 effect of post-exercise protein-carbohy...

BACKGROUND Pancreatic cancer is often accompanied by cachexia, a syndrome of severe weight loss and muscle wasting. A suboptimal response to nutritional support may further aggravate cachexia, yet the influence of nutrition on protein kinetics in cachectic patients is poorly understood. METHODS Eight cachectic pancreatic cancer patients and seven control patients received a primed continuous ...

In healthy individuals, postexercise protein supplementation increases muscle protein anabolism. In patients with muscular dystrophies, aerobic exercise improves muscle function, but the effect of exercise on muscle protein balance is unknown. Therefore, we investigated 1) muscle protein balance before, during, and after exercise and 2) the effect of postexercise protein-carbohydrate supplement...

lanczos-type algorithms are well known for their inherent instability. they typically breakdown occurs when relevant orthogonal polynomials do not exist. current approaches to curing breakdown rely on jumping over the non-existent polynomials to resume computation. this may have to be used many times during the solution process. we suggest an alternative to jumping, which consists of restarting...

background: in this study we investigated the differences of functional gait and balance measures between patients with chronic stroke with different level of concern about falling. methods: fifty-four patients with chronic stroke participated in this observational, cross-sectional study. the level of concern relating to falls was assessed by using the falls efficacy scale-international. thirty...

biofiltration of triethylamine (tea) vapor used as a catalyst in casting operations was evaluated in this study. the unit consisted of a 6-l three-stage biofilter containing a mixture of compost and wood chips (40:60 v/v) as the filter medium. seed microbial population from municipal activated sludge was acclimated for a period of three weeks prior to the actual experimental runs. in the startu...