The increasing prevalence of multiresistant Gram-negative bacteria of the Enterobacteriaceae family in Europe is a worrisome phenomenon. Extended spectrum betalactamase-producing Escherichia coli strains are widespread in the community and are frequently imported into the hospital. Of even more concern is the spread of carbapenem-resistant strains of Klebsiella spp. from regions where they are ...

Background and Objectives: Since the fluoroquinolones are the broad-spectrum antibiotics, they affect both Gram-negative and Gram-positive bacteria. These antibiotics are widely prescribed by physicians. As a result, some bacteria, especially Enterobacteriaceae, have shown a resistance to this family of antibiotics. The current study a...

Resistance to contemporary broad-spectrum beta-lactams, mediated by extended-spectrum beta-lactamase (ESBL) enzymes, is an increasing problem worldwide. The Etest (AB Biodisk, Solna, Sweden) ESBL screen uses stable gradient technology to evaluate the MIC of ceftazidime alone compared with the MIC of ceftazidime with clavulanic acid (2 micrograms/ml) to facilitate the recognition of strains expr...

ISSN 2330-4456 Abstract Objectives: Neonatal sepsis with extended-spectrum betalactamase (ESBL) producing microorganisms is recognized increasingly in recent years. ESBL can be produced by various bacterial strains. This study was conducted to determine the prevalence of ESBL producing pathogens in neonatal sepsis and its impact on clinical outcome. Materials and Methods: A study was carried ou...

BACKGROUND It is important to identify patients who are at risk for infections with extended-spectrum β-lactamase (ESBL)-producing bacteria in order to reduce mortality, to avoid spread of resistant bacteria in hospitals, and to minimize the number of patients receiving unnecessary treatment with broad-spectrum antibiotics. A case-control survey among Swedish patients was performed at Skåne Uni...

Background Trimethoprim-sulfamethoxazole (TMP-SMX) is a broad spectrum antimicrobial agent and also reduces the mortality among adults and children when used as prophylaxis against opportunistic infections in HIV infected patients. Drug resistant to TMP-SMX along with Extended spectrum b-lactamase (ESBL) production among Enterobacteriaceae is creating major therapeutic problem in clinical setti...

Escherichia fergusonii is a Gram-negative rod which belongs to the family Enterobacteriaceae. Though known to behave as a commensal organism in the gut of warm-blooded animals, knowledge regarding its natural habitat mostly remains unclear. E. fergusonii is very rarely recovered from clinical specimens and it has recently emerged as the causative agent of wound, biliary and urinary tract infect...

Results Among 979 strains isolated during this period, 10.82 % (106) were ESBL producers. These bacteria were isolated in 94.33% in the inpatients specimens. Their distribution was essentially in the ICU (22.64%),the surgery (20.75%) and the pediatrics 21.21%.They were more frequently isolated from urines (36.79%), pus (33%), peritoneal liquid (15,15%)and bacteremia (12,26%).This betalactamase ...