Animals dosed orally with nitrite (1.5 X 10(-3) mol/kg) and nonyl dimethylbenzylammonium bromide (2.9 X 10(-4) mol/kg) exhibit liver damage within two hours; cetyl trimethylammonium bromide plus nitrite was not significantly hepatotoxic. Both nonyl dimethylbenzyl ammonium bromide and cetyl trimethylammonium bromide were demethylated by rat-liver microsomal preparations; substrate concentrations...

Six different bromide salts - tetraethylammonium bromide ([N2,2,2,2]Br, Br), 1-ethyl-1-methylpiperidinium bromide ([C2MPip]Br, Br), 1-ethyl-1-methylpyrrolidinium bromide ([C2MPyrr]Br, Br), 1-ethyl-3-methylimidazolium bromide ([C2MIm]Br, Br), 1-ethylpyridinium bromide ([C2Py]Br, Br), and 1-(2-hydroxyethyl)pyridinium bromide ([C2OHPy]Br, Br) - were studied in regards to their capacity to form pol...

Increased serum bromide may result from the ingestion of various drugs and from environmental exposures. Chloride methods that are less susceptible to bromide interference have a clinical disadvantage in that they are less likely to arouse suspicion in cases of bromide toxicity. When there is a clinical suspicion of bromide toxicity, differences among various analyzers in the amount of interfer...

OBJECTIVE To critically evaluate and summarize available information on the safety of potassium bromide in dogs. DESIGN Systematic review. SAMPLE 111 references reporting safety information relevant to potassium bromide published between 1938 and 2011. PROCEDURES PubMed searches without date limitations were conducted with the terms "potassium bromide" and "sodium bromide" in December 200...

In the title compound, C(12)H(24)N(+)·Br(-), both cyclo-hexane rings adopt the usual chair conformation. The cation and anion are linked by N-H⋯Br hydrogen bonds into a linear chain running along the c axis.

benzyltriphenylphosphonium bromide (btpb) has been applied as an efficient catalyst for the preparation of bis(indolyl)methanes (bims) via electrophilic substitution of indoles with aldehydes in the absence of solvent.

The crystal structure of the title compound, C(11)H(18)N(+)·Br(-), has been determined as part of an ongoing study of the influence of the alkyl chain length on amphiphilic activity of quaternary ammonium salts. The title salt forms a three-dimensional network of ionic contacts through weak C-H⋯Br hydrogen bonds, with donor-acceptor distances in the range 3.757 (2)-3.959 (2) Å, in which methyl ...

Therapy with bronchodilators forms the pharmacologic foundation of the treatment of patients with COPD. Bronchodilators can significantly lessen dyspnea, increase airflow, improve quality of life, and enhance exercise performance. While bronchodilators decrease airway resistance and lessen dynamic hyperinflation in patients with COPD, they have not been shown to alter the rate of decline in FEV...

Condensation and cyclization of 5-hydroxy- 1,2,4- thiadiazol-2-yl hydrazine 1 with pyruvic acid, phenacyl bromide, propargyl bromide and ally1 bromide afforded compounds 2,5,7 3, 4 ,6 and 8 respectively, Reaction of 1 with epichforohydrine afforded 4-hydroxy-N-[5-hydroxy- 1 ,3,4-thiadiazoly1] pyrazolidine 9