OBJECTIVE To identify the allergen(s) responsible for mid April-mid May nasobronchial allergy seen in North India. DESIGN Case control study. SETTING Children living in and around Chandigarh (urban, rural). SUBJECTS 39 children suffering from wheat harvest period (mid April-mid May) respiratory allergy along with randomly selected controls. METHODS Aerobiological surveys were done from ...

Nickel sulphate more frequently determines allergic dermatitis due to contact (contact eczema); less known are nasal inflammation (rhinitis) and bronchial asthma caused by nickel sulphate. Sporadic cases, often related to patients' work have been reported in the literature. The research described herein refers to 20 patients presenting clear nickel allergy with rhinitis (associated in 11 cases ...

BACKGROUND Allergic rhinitis and asthma may be associated, bronchial hyperreactivity (BHR) is quite common in AR patients. It has been reported that allergen bronchial challenge induces nasal inflammation. Methacholine (MCH) is a stimulus able to elicit BHR. There is no study that investigated the effect of MCH bronchial challenge on the nose. OBJECTIVE The aim of this study was to evaluate w...

Rupture of the bronchus has become more common in the last decade, mainly due to an increase in road traffic accidents. In spite of this increase it is still relatively rare, and most thoracic surgeons do not have the personal experience of treating more than two or three cases in their life-time. In 1947 Kinsella and Johnsrud reviewed the world literature on intrathoracic rupture of the trache...

In order to determine the effect of drugs on bronchial hyperreactivity in subjects with asthma, 12 atopic asthmatic volunteers underwent bronchial challenge with either histamine or methacholine on three separate days. Before the challenges no medication was given on the first day, on the second 400 microgram of aerosol fenoterol and on the third 5 mg of oral fenoterol were administered. The ae...

Two carpenters developed rhinitis, conjunctivitis, bronchial wheezing, and dyspnoea while using obeche (Triplochiton scleroxylon, African maple) at their work while they built saunas. Skin prick tests showed an immediate reaction, specific IgE to obeche was detected in their serum, and bronchial provocation test with obeche gave an immediate reaction with decrease of FEV1 and PEF values. The sy...

We have studied the bronchial hyperresponsiveness (BHR) of children with normal controls and asthma by methacholine inhalation challenge, using a forced oscillation method. Four parameters, respiratory conductance (Grs), bronchial responsiveness (PD35Grs), bronchial sensitivity (Dmin) and reactivity (SGrs) were studied. There were three patterns of dose-response curves identified in this study,...

STUDY OBJECTIVE We evaluated whether aging may produce changes in bronchial hyperresponsiveness, risk of enhanced bronchoconstriction, and changes of bronchoconstriction perception. SETTING Each subject underwent a methacholine bronchial challenge. Methacholine challenge was stopped when one of the following conditions occurred: (1) plateau of bronchoconstriction; (2) decrease of FEV(1) > 40%...