OBJECTIVE(S) The aims of present study were to elucidate the effect of NaHS as a H2S donor on precontracted rat trachea smooth muscle, role of epithelium and nitric oxide in this action. MATERIALS AND METHODS Tracheal rings from male adult Wistar rats were isolated and mounted in an organ bath containing Krebs-Henseleit solution under 1.5 g resting tension and contractions were recorded isome...

Achillea millefolium Linn. (Asteraceae) is used in folk medicine for the treatment of overactive cardiovascular and respiratory ailments. This study describes its hypotensive, cardio-depressant, vasodilatory and bronchodilatory activities. The crude extract of Achillea millefolium (Am.Cr) caused a dose-dependent (1-100 mg/kg) fall in arterial blood pressure of rats under anaesthesia. In spontan...

Carum carvi (CC) is a grassy plant which is believed to have several therapeutic effects, including anti-asthmatic properties. We have therefore studied the bronchodilatory and anticholinergic effects of this plant. The bronchodilatory effects of the aqueous extract (AE), macerated extract (ME), essential oil (EO), and 4µM theophylline (T) in comparison with saline (S) were examined by the...