Pathogenic brucellae are the agent of brucellosis, a disease that causes abortion and infertility in natural hosts such as sheep, goats, or cattle. Brucella melitensis, Brucella abortus, and Brucella suis are the most pathogenic Brucella species for humans and also the most relevant bacteria involved in economical loses and in animal and human health problems. In addition, these Brucella repres...

Abstract Brucella spp. are facultative intracellular bacterial pathogens that have the ability to survive and multiply in professional nonprofessional phagocytes. Successful invasion chronic persistence indicate manipulates various host cellular processes create a replication permissive niche. The essential mechanisms factors support of remain poorly understood. RNA interference (RNAi) is poten...

Multilocus enzyme electrophoresis (MLEE) of 99 Brucella isolates, including the type strains from all recognized species, revealed a very limited genetic diversity and supports the proposal of a monospecific genus. In MLEE-derived dendrograms, Brucella abortus and a marine Brucella sp. grouped into a single electrophoretic type related to Brucella neotomae and Brucella ovis. Brucella suis and B...

Total knee arthroplasty (TKA) is a rewarding procedure in patients with hemophilia and end stage knee hemophilic arthropathy. However, this procedure might be associated with complications such as infection. There periprosthetic joint infection in patients with hemophilia is very well known, though we are not aware of any previous report on Brucella infection in this group of patients. Here, we...

Objective: Brucellosis is a systemic zoonosis that affects various organs or body systems and can mimic many diseases. Symptoms range from acute febrile illness to chronic clinical manifestations with severe complications. In our study, we investigated the relationship between bacteremia laboratory findings, complications in patients brucellosis.
 Material Methods: Two hundred twenty-three...

With the aim of developing quantitative PCR methods for the detection and differentiation of Brucella species, the genomes of Brucella ceti, Brucella inopinata, Brucella netotomae, and Brucella suis biovar 4 were sequenced and analyzed.

INTRODUCTION Brucella is a zoonotic infection commonly diagnosed by isolation of the organism from blood culture or positive serological testing. It is an uncommon cause of a pyrexia of unknown origin in the United Kingdom. CASE PRESENTATION We describe the case of a 14-year-old girl with no history of travel who presented with pyrexia, weight loss, arthralgia, multiple splenic abscesses and ...

Brucellosis is a zoonotic disease common in developing countries. Vascular complications, including arterial and venous, associated with Brucella infection have rarely been reported. A case of deep venous thrombosis (DVT) developing after a diagnosis of acute brucellosis in a young milkman is presented. A 26-year-old man presented with pain in the right leg. The patient's medical history includ...

introduction brucellosis is a common zoonotic disease which has a wide spectrum of clinical manifestations and complications in humans. brucellosis is an endemic disease in iran. the aim of this case report was to introduce acute hepatitis as a rare complication of acute brucellosis. case presentation first case, a 25-year-old man, who complained from fever, chillness, nocturnal sweating, nause...

BACKGROUND Biomedical ontologies are representations of classes of entities in the biomedical domain and how these classes are related in computer- and human-interpretable formats. Ontologies support data standardization and exchange and provide a basis for computer-assisted automated reasoning. IDOBRU is an ontology in the domain of Brucella and brucellosis. Brucella is a Gram-negative intrace...