نتایج جستجو برای: buccal tablet
تعداد نتایج: 41501 فیلتر نتایج به سال:
The treatment of breakthrough pain (BTP), a transitory exacerbation of pain that occurs on a background of otherwise-controlled, persistent pain, requires an opioid formulation and/or method of administration that can provide rapid and extensive systemic exposure. Fentanyl buccal tablet (FBT; FENTORA((R)), Cephalon, Inc.) employs OraVescent((R)) drug delivery technology, which enhances the rate...
Objective: The Losartan potassium mucoadhesive buccal tablet were prepared using mucoadhesive polymers such as Carbopol 940P, pectin, sodium CMC, Sodium alginate, HPMC K4M, HPMC K15M and HPMC K100M in alone and in combination as release retarding agent to prolong the drug release and to avoid first pass metabolism. Methods: The mucoadhesive buccal tablets were prepared by direct compression met...
The study is related to the formulation and evaluation of mucoadhesive buccal tablets Anastrozole enhance its bioavailability by avoiding 1st pass effect. succeeded in developing containing two layers (mucoadhesive backing layer) a design that permits unidirectional release drug. Tablets were prepared double direct compression method using (carbopol 934) as primary polymer, Sod.alginate, Na CMC...
The aim of this study was to develop a freeze-dried buccal tablet for the rapid delivery of naloxone in opioid overdose. The tablet composition was optimized to produce an amorphous matrix, which was confirmed by the absence of peaks associated with crystallinity observed by differential scanning calorimetry and powder X-ray diffraction. Tablets with high gelatin content lacked adequate porosit...
1. Yong CS, Jung JH, Rhee JD, Kook KC, Choi HG. Physicochemical characterization and evaluation of buccal adhesive tablets containing omeprazole. Drug Develop Ind Pharm 2001;27:447-55. 2. Martindale-The complete drug reference. In: Sweetman SC, editor. London: Pharmaceutical Press; 2005. 3. Clarke’s Analysis of Drugs and Poisons. In: Moffat AC, Osselton MD, Widdop B, editors. London: Pharmaceut...
Despite the availability of modern insulin injection devices with needles that are so sharp and thin that practically no injection pain takes place, it is still the dream of patients with diabetes to, for example, swallow a tablet with insulin. This is not associated with any pain and would allow more discretion. Therefore, availability of oral insulin would not only ease insulin therapy, it wo...
The buccal route does not have any disadvantages when compared to the oral route of prostaglandin administration. The incidence of vomiting (25%) described for the oral route by other workers is similar.2 3 The buccal route also has the advantages of oral drug administration. These are staff convenience and patient comfort, the latter being without the discomfort of an intravenous infusion and ...
In the present investigation an attempt has been made to design efficacious and prolonged release mucoadhesive tablet of salbutamol sulphate using various polymers to avoid the first pass metabolism to reduce dossing frequency and to improve patient compliance. Mucoadhesive buccal tablet of salbutamol sulphate were fabricated with objective of avoiding first pass metabolism and to improve its b...
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