Pseudo-benzylic substitution is an important reaction in the ferrocene series, especially to obtain ligands for catalysis. Herein, we described new reactions conditions, using fluorinated alcohols as both solvent and promoter, able deliver iodoferrocene derivatives faster than classical solvents. Various N, O, P C-nucleophiles were found compatible with this transformation which occurs full ret...

N,N',N''-trimethyltribenzo-1,4,7-triazacyclononatriene has been synthesized via sequential palladium-catalyzed Buchwald-Hartwig N-arylation reactions affording the 9-membered triaza o-cyclophane in 35% overall yield. An X-ray crystal structure shows the new cyclophane to have a C2-symmetric saddle conformation, as compared to the crown conformation exhibited by the related carbocyclic cyclotriv...

The synthetic route toward novel tricyclic, nitrogen-containing system is disclosed. Three compounds possessing structural features of 1,2,3,4-tetrahydroquinoxaline and decahydropyrido[3,4-b]pyrazine are synthesized starting from readily available precursors in six or seven steps, which the last three four steps respectively diastereoselective. Key reaction include N-acylation, Hofmann rearrang...

Rapid development of the copper-catalyzed amination aryl halides in beginning 21st century, known as Renaissance Ullmann chemistry, laid foundations for use this method a powerful tool construction C(sp2)-N bond and became rival Buchwald–Hartwig reaction. Various applications approach are well-documented number comprehensive more specialized reviews, overview form personal account Cu-catalyzed ...

Cyclic hexamers consisting of a 4-octyl, 4-octyloxy and 4-(2-ethylhexyloxy)triphenylamine unit were synthesized via Buchwald-Hartwig cross coupling reaction using A-A, B-B type monomers in order to avoid the formation other cyclic oligomers such as pentamer heptamer. Unlike different size oligomers, all we examined showed clear cold crystallization 165-240°C DSC thermograms. Resulting character...