BACKGROUND Chemotherapy induced nausea and vomiting (CINV) is a side effect, and has negative effect on quality of life and continuation of chemotherapy. Despite new regimen and drugs, the problems still remain and standard guidelines, effective treatment and supportive care for refractory CINV are still not yet established. Persian medicine, the old Iranian medical school, offer Persumac (prep...

Background & Aims: Bunium persicum Boiss. Belongs to Apiaceae family and its fruit contains high level of essential oils used as native medicinal plant in traditional medicine. Methods: The essential oil of Bunium persicum (EOBP) was extracted by Clevenger apparatus using hydrodistillation. Lethal dose, 50% (LD50) was calculated based on Lorke’s method. Effects of EOBP (20- 80 mg/kg) on upper g...

Black zira (Bunium persicum) is a medicinal plant and spice, naturally grows in Iran. The aim of this study was to investigate the combined effects of different concentrations of Bunium persicum essential oil (EO; including 0, 0.08, 0.16 and 0.24%), three incubation temperatures (15, 25 and 35˚C), three levels of pH (5, 6 and 7 adjusted by hydrochloric acid), and three inoculum size (10(2), 10(...

Bunium is one of the interested genus that grow in different region Iraq, it within family Umbelliferae (Apiaceae), and species this have a considerable fruit characteristics. The were chosen study are: B. brachyactis (Post) H. Wolff, caroides (Boiss.) Hausskn. Ex Bornm., chaerophylloides (Regel& Schmalh.) Drude, rectangulum Boiss. & Hausskn., verruculosum C.C.Towns. avromanum (Boiss.&a...

BACKGROUND The key enzyme in the process of melanin biosynthesis is tyrosinase. Skin hyperpigmentation and browning of foods are undesirable phenomena which tyrosinase represents. Therefore, tyrosinase inhibitors have been used increasingly for medicinal and cosmetic products. OBJECTIVES In this study, inhibitory effects of four plants including: physalis alkekengi L., Alcea rosea L., Bunium ...

Uranium concentrations in the drinking water samples collected mainly from hand pumps along the Amritsar to Bathinda track are presented. Uranium concentration values in these samples show a wide range of variation depending upon different factors like source, location, depth and local geology etc. The observed uranium content in water samples has been found to be varying from 0.9 ± 0.08 to 63 ...