OBJECTIVE To compare the analgesic efficacy of Bupivacaine 0.25% wound infiltration with Ketorolac incisional infiltration in relieving postoperative pain for first twenty-four hours. METHODOLOGY Analytical, interventional and comparative study was performed on seventy patients, of both sexes, with varied age groups. Patients underwent minor and moderate surgeries, confined to American Societ...

BACKGROUND In the past, the efficacy of local infiltration of liposomal bupivacaine for total hip arthroplasty (THA) patients was in debate. Therefore, this meta-analysis was conducted to determine whether local infiltration of liposomal bupivacaine provides better pain relief after THA. METHODS We searched Web of Science, PubMed, Embase, and the Cochrane Library databases to the April 2017. ...

cision is closely associated with postoperative wound pain [9]. The single umbilical incisions reported in other studies typically reached lengths of 15 to 20 mm. Although postoperative pain has not been a major concern since the introduction of the routine laparoscopic cholecystectomy (LC), supporters of a single-incision LC (SILC) advocate the hypothesis that a reduction in the number of inci...

the purpose of the current study was to determine whether infiltration of bupivacaine in the incision site of midline laparotomy reduces postoperative pain and opioid consumption. fifty-six, 30-60 year-old patients who were undergoing midline laparotomy were enrolled in the present study. the patients were randomly assigned into two groups of control (group c, n = 28) or bupivacaine (group b, n...

background pain following laparoscopy could be due to different causes requiring effective postoperative analgesia. objectives in the present study, we evaluated the combined effect of intraperitoneal infiltration of bupivacaine-meperidine versus intravenous infusion of paracetamol on pain relief after diagnostic gynecologic laparoscopy. conclusions intraperitoneal infiltration of bupivacaine w...

BACKGROUND AND OBJECTIVES The aim of this study was to investigate the effects of saline solution, bupivacaine, lidocaine and tramadol infiltration on wound healing in rats. METHOD Thirty-two male Wistar Albino rats were randomly separated into four groups, receiving 3 mL saline solution in control group (Group C, n=8), 3 mL of 2% lidocaine in lidocaine group (Group L, n=8), 3 mL of 0.5% bupi...

INTRODUCTION In the treatment of patients with symptomatic irreversible pulpitis, endodontic debridement is a predictable method to relieve pain. However, there are clinical situations in which emergency care cannot be provided immediately. An unexplored treatment option in these cases may be the use of a long-acting anesthetic to reduce pain in untreated irreversible pulpitis. Some medical stu...

BACKGROUND Neuropathic pain resulting from diverse causes is a chronic condition for which effective treatment is lacking. The goal of this study was to test whether dexamethasone exerts a preemptive analgesic effect with bupivacaine when injected perineurally in the spared nerve injury model. METHODS Fifty rats were randomly divided into five groups. Group 1 (control) was ligated but receive...

Liposome bupivacaine is a prolonged-release liposomal formulation of bupivacaine indicated for single-dose infiltration into the surgical site to produce postsurgical analgesia of longer duration than traditional local anesthetics. This review summarizes the available data on how volume expansion may impact the analgesic efficacy of liposome bupivacaine. The Phase II and III clinical studies th...

OBJECTIVE To investigate opioid use and pain scores associated with incisional injection of liposomal bupivacaine compared with bupivacaine hydrochloride after laparotomy for gynecologic malignancies. METHODS A retrospective cohort study was conducted to compare abdominal incision infiltration with liposomal bupivacaine with bupivacaine hydrochloride after modification of a pre-existing enhan...