Elevated metabolic rate is a hallmark of the stress response to severe burn injury. This response is mediated in part by adrenergic stress and is responsive to changes in ambient temperature. We hypothesize that uncoupling of oxidative phosphorylation in skeletal muscle mitochondria contributes to increased metabolic rate in burn survivors. Here, we determined skeletal muscle mitochondrial func...

BACKGROUND Abnormal acute pain after burn injury still torments patients severely. In this study, we investigated that one voltage gated sodium channel Nav1.7 plays a vital role in lowering heat pain threshold after burn injury, and the hypothesis that knockdown of Nav1.7 attenuates pain following burn injury. METHODS Sixty eight adult male Sprague-Dawley rats were divided into 4 treatment gr...

Pulse oximeters have become essential devices for evaluating and monitoring patient oxygenation. The probe emits a small amount of heat into the skin in the process of signal detection. Regulations set by the Food and Drug Administration currently limit the maximum allowable temperature of an oximeter probe to 41 degrees C. As a result of the prolonged exposure of extremities to these devices, ...

Hypothermia is a common complication in patients with extensive burns, receiving massive volumes of fluid for resuscitation at ambient temperature. It is therefore important to maintain the body temperature of patients with extensive burns. The present study was performed to evaluate the usefulness of warm fluid for burn injury resuscitation. Ten dogs were used in this study. Full-thickness bur...

230 LLE Review, Volume 96 Introduction In an inertial confinement fusion (ICF)1 experiment, a capsule filled with deuterium (D2) or a deuterium–tritium (DT) fuel is heated by either direct laser illumination or soft-x-ray radiation in a laser-heated hohlraum. The target is compressed to conditions under which thermonuclear fusion occurs. The fusion burn begins with spark ignition of the central...

Burn-in is accepted as a way to evaluate ageing effects in an accelerated manner. It has been suggested that burn-in stress may have a significant effect on the Negative Bias Temperature Instability (NBTI) of subthreshold CMOS circuits. This paper analyses the effect of burn-in on NBTI in the context of a Digital to Analogue Converter (DAC) circuit. Analogue circuits require matched device pair...

In this paper, an axisymmetric model of the human skin is developed to simulate the steady-state temperature distribution during contact with a hot solid. Simulations are carried out using the boundary element method. This study seeks to investigate the feasibility of using the boundary element method in the studies of burn. A sensitivity analysis is carried out to examine the effects of variou...

I wish to report an unusual postoperative burn in a 79 year-old man undergoing a right total hip replacement. A pre-operative lumbar plexus block was performed and general anaesthesia induced. He was placed in the left lateral position with a beanbag to secure him and an axillary roll was placed under the dependent left axilla. The diathermy plate was attached to the left thigh. An upper body f...

background burn is still one of the most devastating injuries in emergency medicine while improvements in wound healing knowledge and technology have resulted into development of new dressings. this study was undertaken to evaluate the healing effect of licorice in pseudomonas aeruginosa infected burn wounds of experimental rat model. methods one hundred and twenty female sprague-dawley rats we...