BACKGROUND The efficacy of Centella asiatica for incision and burn wounds are not fully understood. Here, we report the wound healing activities of sequential hexane, ethyl acetate, methanol, and water extracts of Centella asiatica in incision and partial-thickness burn wound models in rats. METHODS Male Sprague-Dawley rats weighing 250-300 g were randomly divided into incision and burn wound...

BACKGROUND The cause of death in burn patients after 48 hours of hospitalization has been reported to be bacterial infections. Recently, due to the compounds accelerating the healing process and the intense reduction of treatment side effects, medicinal plants are used to cure burn wound infections. This study aims to investigate the medicinal effect of the ethanolic extract of Scrophularia st...

objective- to evaluate the application of carbomer 940 hydrogel on saving zone of stasis in skin burn wound. design- experimental study animals- twenty rats. procedures- after shaving the backs, a ‘comb burn’ was contacted bilaterally on the dorsum of the rats 0.5 cm lateral and parallel to the midline by using a brass probe consisting of four rows (10×20 mm) and three interspaces (5×20 mm). al...

background numerous studies were carried out to develop more sophisticated dressings to expedite healing processes and diminish the bacterial burden in burn wounds. this study assessed the healing effect of nettle extract on second degree burns wound in rats in comparison with silver sulfadiazine and vaseline. methods forty rats were randomly assigned to four equal groups. a deep second-degree ...

Development of metrics for burn care, including healing of skin wounds during the acute phase of treatment, is essential in an environment of decreasing resources and increasing interest in quality and accuracy of medical information. Advantages of consensus metrics include: tracking of trends in care; consistency of care; and correlation of treatment with medical outcomes. For cutaneous burn w...

EROGLU, E., AGALAR, F., ALTUNTAS, I. and EROGLU, F. Effects of GlanulocyteColony Simulating Factor on Wound Healing in a Mouse Model of Burn Trauma. Tohoku J. Exp. Med., 2004, 204 (1), 11-16 ── The effects of burn trauma and granulocyte-colony stimulating factor (G-CSF) treatment on wound healing in a surgical incision model were studied. Sixty adult male mice were used in this study. Under gen...

Aloe vera and Vitis vinifera have been traditionally used as wound healing agents. The present study aimed to investigate the effects of aloe emodin and resveratrol in the burn wound healing procedure. Burn wounds are common in developed and developing countries, however, in developing countries, the incidence of severe complications is higher and financial resources are limited. The results of...

The healing of burn wounds has been widely characterized to be highly intricate, involving processes such as neo-vascularization, granulation, re-epithelialization, inflammation and wound contraction. Various therapies are available for the management of burn wounds; however, a truly effective therapeutic strategy has yet to be identified due to safety issues. The aim of the present study was t...

BACKGROUND Wound healing is widely discussed in the medical literature. This study compared the healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model. METHODS Sixteen rats were randomly assigned to one of two groups, each group 8 rats. A deep second-degree burn on the lower back and 3rd degree burn on upper back of each rat were created with a...

Objective: The role of insulin in the regulation of energy metabolism, protein synthesis, cell differentiation and growth suggests that this hormone could also play an essential role in regulation of wound healing. Consequently, the aim of the present study was to investigate the effects of topical insulin administration on burn wound healing in both non-diabetic and streptozocin-induced diabet...