conclusions non-invasive assessment of hepatic fibrosis could be done using the egy-score. egy-score could differentiate no or early fibrosis (stage f0-f2 metavir) from severe fibrosis or cirrhosis (stage f3 - f4 metavir) with 83.7% accuracy. results combined elevation of ca 19-9 and ca 125 with a summated value > 37 u/ml is predictive of severe hepatic fibrosis or cirrhosis (stage f3-f4 metavi...

endometriosis is an estrogen dependent disease. levels of cancer antigen-125 are significantly higher in women with moderate to severe endometriosis. however, patients with unruptured endometriosis rarely have serum ca-125 levels more than 1000 u/ml. this case report presents a diffuse, unruptured ovarian endometrioma in a 29- year-old woman, leading to an extraordinary high serum ca-125 and ca...

In order to evaluate the specificity of tumor markers in chronic renal failure, we have determined serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19.9 (CA 19.9), carbohydrate antigen 50 (CA 50), alphafetoprotein (AFP), neuron-specific enolase (NSE), prostatic acid phosphatase (PAP), prostatic specific antigen (PSA), squamous cell carcinoma antigen (SCC), carbohydrate antig...

Background Tumor markers have been a valuable tool for decades to aid in the diagnosis, treatment, and monitoring of oncological diseases.
 Objective To retrospectively analyze requisition pattern tumor marker requests at largest tertiary care center eastern Nepal.
 Method A retrospective hospital-based cross-sectional study was conducted obtain data 5 common i.e., Alpha-Fetoprotein (...

BACKGROUND Osteoporosis and tumour-associated antigen (TAA) levels are associated with inflammatory processes, but little remains known about TAA levels and bone mineral density (BMD). AIMS We determined whether or not high-normal TAA levels are associated with a lower BMD in healthy women. METHODS A total of 3769 healthy women were enrolled from the health screening programme over 5 years....

The aim of this study was to assess the incidence of ovarian cancer in the industrial hub of Uttar Pradesh. A total of 50 samples were collected and estimated for CA-125 by Sandwich Method. CA-125 [Cancer antigen 125 or carbohydrate antigen 125 or Mucin 16] is a high molecular mass glycoprotein recognized by the monoclonal antibody OC 125 and encoded by MUC 16 gene. It contains 24% carbohydrate...

Background: Increasing evidence from recent studies has revealed the association of CA125 with the diagnosis of pancreatic cancer, but inconsistent findings have been reported. We aimed to evaluate the diagnostic value of a serum CA125-based diagnostic panel in predicting malignant pancreatic cancer. Materials and Methods: We searched EMBASE, MEDLINE and Web of Science for relevant articles fro...

Serum concentrations of cancer antigen 125 (CA 125) were determined for 373 patients with various liver diseases: 57 with acute hepatitis, 57 with chronic hepatitis, 244 with liver cirrhosis (86 compensated and 158 decompensated), and 15 with primary liver cancer. The antigen was measured simultaneously in the serum and ascitic fluid of 46 of the patients with liver cirrhosis and sequentially i...

Objective: We aimed to evaluate the prognostic role of preoperative serum cancer antigen 125 (CA-125) in endometrioid endometrial for determining cut-off values clinicopathological factors.
 Study design: 161 patients were included study. The inclusion criteria histopathological confirmation and with CA-125 levels measured at most ten days before surgery. association between value variable...