Cytotoxicity of cadmium sulphide, oxide and chloride was tested using A549 and CHO-9 cells. Metabolic activity of cells (MTT test) and cell membrane permeability (NRU test) were used as cytotoxicity endpoints. The results revealed unexpectedly low toxicity of cadmium sulphide as compared to chloride and oxide. This preliminary report does not provide any explanation for this effect, but the res...

The present study was designed to investigate the potential protective effect of Coenzyme Q10 against the testicular toxicity of cadmium in male rabbits. Four groups of animals were used in this study (control, Coenzyme Q10, cadmium chloride-treated (5 mg/kg), cadmium chloride plus Coenzyme Q10 (10 mg/kg) for 30 days). Results showed normal testicular tissue in control and coenzyme Q10 groups. ...

OBJECTIVE To study the effects of cadmium on hepatocellular DNA damage, expression of proto-oncogenes c-myc, c-fos, and c-jun as well as apoptosis in rats. METHODS Cadmium chloride at the doses of 5, 10, and 20 micromol/kg was given to rats by i.p. and there were 5 male SD rats in each group. Hepatocellular DNA damage was measured by single cell gel electrophoresis (or comet assay), while exp...

Cadmium Chloride is a well known teratogen compared to other metals. Cadmium affects placental function, may cross the placental barrier and modify fetal development. In this study, 12 female wistar albino rats weighted between 180-200gr were used. They were divided into two groups as experimental and control groups each comprising 6 female animals. 2mg/kg/day cadmium chloride dissolved in 1ml ...

abstract aims: chemical precipitation is a simple, efficient, and cost-effective method for eliminating heavy metals found in landfill leachate. the aim of the present study was to compare the efficacy rates of cadmium removal with the coagulants like poly aluminum chloride and lime using chemical precipitation method. materials & methods: in this experimental study, the raw studied samples wer...

This investigation aimed to examine the protective function of vitamin E on rat bone marrow mesenchymal stem cells (MSCs) treated with cadmium chloride. Rat bone marrow MSCs were extracted using flashing-out and cultured in DMEM containing 10% FBS and 100 U/ml Pen/Strep. At the end of the third passage, cells were divided into 4 groups including control, cadmium chloride, cadmium chloride + vit...

The present study aimed to assess the protective role of selenium against cadmium induced hepatotoxicity. The rats were given subcutaneous doses of 1mg/Kg body weight of either normal saline or cadmium chloride or sodium selenite or cadmium chloride plus sodium selenite on alternate days for four weeks. The results showed that cadmium treatment increased hepatic levels of lipid peroxidation, DN...

background edible salt is the most commonly used food additive worldwide. therefore, any contamination of table salt could be a health hazard. objectives the present study aimed to determine the levels of heavy metals in table and bakery refined salts. materials and methods eighty-one table refined salt samples and the same number of bakery refined salt samples were purchased from retail market...

The effect of cadmium chloride on green gram (Vigna radiata Linn.) was studied using the parameters like carbohydrates, protein, chlorophyll and oxidative enzymes like superoxide dismutase, catalase and peroxidase of leaves inorder to know the possible involvement of cadmium metal in the generation of oxidative stress. Results obtained in this work showed that the application of cadmium decreas...

Cadmium is a dangerous occupational and environmental toxin. It accumulates in the human organism mainly in liver and kidneys. Cadmium half-life is about 10 years, so the symptoms of cadmium intoxication may occur several years after the exposure. Until now in treating intoxication with this metal chelating compounds have been used, burdened with numerous undesirable symptoms. In our investigat...