1. Fura-2 imaging was used to measure the effects of glutamate on caffeine-sensitive Ca2+ stores in neurons of the avian cochlear nucleus, n. magnocellularis (NM). 2. On average, 100-mM caffeine stimulated a 250-nM increase in intracellular calcium ion concentration {[Ca2+]i} in Ca(2+)-free media; 1-mM glutamate significantly attenuated caffeine-stimulated Ca2+ responses. 3. The metabotropic gl...

Animal-pollinated plants face a common problem, how their defensive anti-herbivore compounds may impair or alter pollinator behavior. Evolution has tailored multiple solutions, which largely involve tolerance manipulation, to the benefit of plant, not removal these from pollen nectar. The tea Camilla sinensis, is famous for caffeine and polyphenols (TP) that it produces in its leaves. However, ...

Abstract The aim of the research was to evaluate response three tropical species (Heliconia psittacorum, Ciperus haspan, Hedychium coronarium), respect their tolerance and removal capacity pharmaceutical personal care products (PPCPs), namely acetylsalicylic acid, ibuprofen, methyl hydrojasmonate (cis – MDJM), galaxolide, tonalide, caffeine, naproxen, ketoprofen, diclofenac. study undertaken in...

Coffee is a major source of caffeine, which has been shown to have a number of behavioural effects. For example, caffeine increases alertness, improves sustained attention and psychomotor performance. These beneficial effects often increase with dose (within the limits consumed by the majority of the population). Caffeine has less effect on memory but has recently been shown to improve retrieva...

Abstract Caffeine is a well-known central nervous system stimulant, which can cause anxiety, insomnia and nervousness. Domestic wastes of caffeinated drinks, beverages chocolates are the major sources for entry caffeine in environmental system. has been widely detected natural water resources. The current study describes method efficient removal from aqueous solution by laboratory scale dielect...

BACKGROUND The aim of this work was to study the biological treatment a synthetic wastewater containing emerging contaminants. 95-day experiment conducted in an 81 L continuous flow conventional activated sludge apparatus consisting anoxic and aerobic reactors with internal recycling, clarifier recycling. Real from municipal plant Nur-Sultan city used. degradation efficiencies caffeine, metroni...

The mode of action of papaverine on smooth muscle relaxation was examined through analyzing its effects on caffeine-induced contraction of guinea pig taenia coli, which might be due to calcium ion mobilized from intracellular store sites. Caffeine contraction induced in normal solution at 32 degrees C was decreased in the presence of papaverine but increased after the removal of papaverine, and...

The removal of chromosomes from recipient oocytes is one of the key steps in nuclear transfer cloning. Although microtubule interrupters have been successfully used for oocyte enucleation, their potential side effect on oocyte developmental potential should be considered, and less harmful drugs should be explored for chemical-assisted enucleation. Based on our previous findings that any maturat...

Treatment of 9L and 9L-2 cells, which are, respectively, sensitive and resistant to 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), with various concentrations of BCNU followed by treatment with 1 mM caffeine potentiated BCNU cytotoxicity by 10-fold with dose modification factors of 1.5 to 1.7. The synergistic effect of caffeine on cellular toxicity diminished when caffeine was added 6 to 24 h aft...

Caffeine is a first-line option for the neonatal intensive care management of apnea prematurity (AOP) in preterm infants. This first study literature to evaluate cost effectiveness off-label high dose (HD) caffeine versus approved standard lower (LD) treatment AOP neonates. From hospital perspective Hamad Medical Corporation (HMC) Qatar, this was cost-effectiveness analysis based on conventiona...