Francisella tularensis, the Gram-negative bacterium that causes tularemia, produces a high molecular weight capsule that is immunologically distinct from Francisella lipopolysaccharide but contains the same O-antigen tetrasaccharide. To pursue the possibility that the capsule of Francisella live vaccine strain (LVS) has a structurally unique lipid anchor, we have metabolically labeled Francisel...

Shigella is the leading cause for dysentery worldwide. Together with several virulence factors employed for invasion, the presence and length of the O antigen (OAg) of the lipopolysaccharide (LPS) plays a key role in pathogenesis. S. flexneri 2a has a bimodal OAg chain length distribution regulated in a growth-dependent manner, whereas S. sonnei LPS comprises a monomodal OAg. Here we reveal tha...

An osmotic, oral, controlled-release capsule is described. This capsule provides drug delivery at fixed delivery rates (T(80%)=6 or 14h) independent of drug properties (e.g., solubility) or drug loading, thereby allowing rapid development of investigational or commercial drugs, especially for proof-of-concept type clinical studies. The capsule body and cap are prepared with cellulose acetate an...

In this work it is demonstrated, for the first time, that it is feasible to develop, using the electrospraying technique, low molecular weight carbohydrate-based capsule morphologies from aqueous solutions through the rational use of surfactants. Two different low molecular weight carbohydrate polymers were used, a maltodextrin and a commercial resistant starch. The solution properties and subs...

Tracking a capsule endoscope location is one of promising application offered by implant body area networks (BANs). In this paper, we pay attention to a particle filter algorithm with received signal strength indicator (RSSI)-based localization in order to solve the capsule endoscope location tracking problem, which assumes a nonlinear transition model on the capsule endoscope location. However...

this study was conducted to evaluate the effect of foliar micronutrients cu, mg and b on quantitative traits in two sesame crop year 1394 was performed farmer field. a split plot experiment in randomized complete block design with three replications. the main factor includes four operating cu sulfate solution, mg sulfate, b sulfate and control (water) and subplots consisted of two sesame (uniqu...

The present experiment was carried out during Kharif, 2019 at Jawaharlal Nehru krishi Vishwavidyalaya, Jabalpur, Madhya Pradesh, India. A total of 500 accessions were evaluated and observations recorded on twelve traits viz., days to flower initiation, fifty percent flowering, maturity, plant height (cm), number primary branches per plant, secondary capsules seeds capsule, capsule length 1000 s...